ReviewThe Indian journal of medical research2026
Psychosocial challenges of drug-resistant tuberculosis: A qualitative study in Deoghar, Eastern India.
Review in The Indian journal of medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and objectives Despite therapeutic advancements, patients with drug-resistant TB (DR-TB) experience substantial psychosocial challenges that adversely affect treatment adherence and outcomes. Limited research has explored these psychosocial barriers. This study aimed to explore the psychosocial challenges encountered by DR-TB patients from diagnosis through treatment completion. Methods A cross-sectional qualitative study was conducted in the department of Pulmonary Medicine at a tertiary care hospital in eastern India from November to December 2023. Using criterion sampling, 20 DR-TB patients who had successfully completed treatment were recruited. Semi-structured, face-to-face interviews were conducted in Hindi, audio-recorded, transcribed verbatim, and thematically analysed using QDA Miner Lite software following Braun and Clarke's six-step framework. Results Six major themes emerged: (i) Diagnosis-related challenges such as delays, lack of awareness, and misguidance; (ii) Physical and mental health impact, including severe drug-related side effects leading to distress and suicidal thoughts; (iii) Emotional instability, marked by fear, anxiety, and hopelessness; (iv) Family isolation and disruption of social relationships due to stigma and misconceptions; (v) Lack of social support, resulting in discrimination and reduced self-esteem; and (vi) Financial burden, including job loss, treatment-related costs, and debt. Interpretation and conclusions Psychosocial barriers substantially influence treatment adherence and overall well-being among DR-TB patients. Integrating mental health services, strengthening counselling, addressing stigma, and providing financial assistance within the National TB Elimination Program (NTEP) are essential to improve patient support, adherence, and clinical outcomes.
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