ArticleMusculoskeletal care2026
The Effect of an Autoimmune Protocol (AIP) Diet in Adults With Rheumatoid Arthritis: A Single Arm Crossover Pilot Feasibility Study.
Article in Musculoskeletal care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Exploring participant experiences with the autoimmune protocol (AIP) diet in rheumatoid arthritis: a longitudinal qualitative study.Journal of nutritional science · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndividuals with rheumatoid arthritis (RA) often ask whether dietary changes or food exclusions can reduce symptoms. The Autoimmune Protocol (AIP) diet, an elimination-based approach, is popular on social media, with anecdotal reports of benefit, but lacks clinical evaluation in RA.
objectivesTo assess the feasibility and effectiveness of an AIP diet on patient-reported outcomes (PROs) in adults with RA.
methodsIn this single-arm, open-label pilot study, nine adults with RA followed their usual diet for 4 weeks and then an 8-week AIP diet in a free-living context. Weekly PRO measures included the Routine Assessment of Patient Index Data 3 (RAPID3) and RA Impact of Disease (RAID) as primary outcomes. Secondary outcomes included 3-day weighed food records and biometric measurements (weight and waist circumference) collected at baseline and every 4 weeks. Adherence and ease of implementation were recorded weekly.
resultsNine participants (7 females, 2 males, aged 40-63 years) completed the intervention. From baseline to end week 12, mean RAPID3 scores decreased from 2.73/10 (range 0.2-5.37) to 0.99 (0-2.5). Four participants demonstrated a clinically meaningful reduction and three others reached remission from low disease activity. Mean RAID scores decreased from 3.13/10 (0.1-6.35) to 1.02 (0-2.96). Fatigue, sleep and pain improved. Mean body mass index reduced from 26.3 kg/m
conclusionsAn 8-week AIP diet was associated with improvements in PROs in seven of nine participants. These pilot findings support further controlled trials to confirm efficacy and explore mechanisms as a potential adjunct therapy for RA.
trial registrationNumber ACTRN12624001391561. https://www.anzctr.org.au/ACTRN12624001391561.aspx.
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