Evidence map›Paper›PMID 41934104›Full record

ReviewNursing open2026

Incidence and Risk Factors of Delayed Chemotherapy-Induced Nausea and Vomiting Among Adult Patients: A Cross-Sectional Study.

Mimi Zheng, Qi Zhang, Liping Ni, Zheng Zheng, Ying Wang, Yiwen Chen, Jing Huang, Jian Gao, Quanlei Li, Yuxia Zhang

Abstract readReview
In one paragraph

Review in Nursing open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mimi ZhengNursing Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Qi ZhangNursing Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.ORCID https://orcid.org/0009-0007-6705-9073
Liping NiNursing Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Zheng ZhengNursing Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Ying WangNursing Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Yiwen ChenNursing Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Jing HuangNursing Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Jian GaoNutrition Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
Quanlei LiSchool of Nursing, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, People's Republic of China.ORCID https://orcid.org/0000-0001-5193-3247
Yuxia ZhangNursing Department, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.ORCID https://orcid.org/0000-0003-4419-7004

Funding

Key Weak Discipline Development Fund at Zhongshan Hospital, Fudan University XK-082-007
6 · The paper itself

Abstract

aimTo assess the incidence of delayed chemotherapy-induced nausea and vomiting (CINV) and identify key risk factors among adult patients.

designA descriptive cross-sectional design.

methodsA total of 326 adult patients undergoing chemotherapy were recruited using consecutive sampling from a nearly 4000-bed tertiary general hospital in Shanghai, China, between July 2023 and April 2024. Demographic and health status data were collected within 24 h of patient admission. Clinicopathologic information was retrieved from nursing documents and electronic medical records. Delayed CINV was measured on the third day post-chemotherapy via telephone interviews using the Common Terminology Criteria for Adverse Events (CTCAE 5.0). Statistical analyses included univariate analysis, random forest modelling, least absolute shrinkage and selection operator (LASSO) analysis and binary logistic regression.

resultsAmong 326 participants, 113 (34.7%) reported delayed nausea and/or vomiting, with 32.2% (n = 105) experiencing delayed nausea and 13.2% (n = 43) experiencing delayed vomiting. The step-by-step analysis identified anxiety, motion sickness and high emetogenicity of chemotherapy agents as key risk factors for delayed CINV. Post hoc analysis showed that body mass index (BMI) and history of delayed nausea or vomiting during previous chemotherapy cycles emerged as important predictors that should be considered when assessing the risk of delayed CINV.

conclusionsHealth care providers should be vigilant in recognising patients at high risk for delayed CINV. Early and targeted prophylactic interventions are recommended to mitigate the risk of delayed CINV. REPORTING

methodThe study followed the STROBE checklist. PATIENT OR PUBLIC CONTRIBUTION: No patient or public contribution.

Indexed as

Antineoplastic AgentsNauseaVomitingAdultAgedChinaCross-Sectional StudiesFemaleHumansIncidenceMaleMiddle AgedNeoplasmsRisk FactorsTime FactorsAntineoplastic Agentscancerchemotherapydelayed nausea and vomitinginfluencing factornursingpatient reported outcome measures

Identifiers

PMID41934104
PMCPMC13052135

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.