Evidence map›Paper›PMID 41933527›Full record

ArticlePoultry science2026

Genome-wide association study of molecular markers related to keel length in a specialized strain of yellow feathered broilers.

Y J Tu, Y F Liu, M Zhang, X J Ju, Y J Shan, G G Ji, J T Shu

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Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Y J TuKey Laboratory for Poultry Genetics and Breeding of Jiangsu Province, Yangzhou 225125, Jiangsu, China; Jiangsu Institute of Poultry Science, Yangzhou 225125, Jiangsu, China.
Y F LiuKey Laboratory for Poultry Genetics and Breeding of Jiangsu Province, Yangzhou 225125, Jiangsu, China; Jiangsu Institute of Poultry Science, Yangzhou 225125, Jiangsu, China.
M ZhangKey Laboratory for Poultry Genetics and Breeding of Jiangsu Province, Yangzhou 225125, Jiangsu, China; Jiangsu Institute of Poultry Science, Yangzhou 225125, Jiangsu, China.
X J JuKey Laboratory for Poultry Genetics and Breeding of Jiangsu Province, Yangzhou 225125, Jiangsu, China; Jiangsu Institute of Poultry Science, Yangzhou 225125, Jiangsu, China.
Y J ShanKey Laboratory for Poultry Genetics and Breeding of Jiangsu Province, Yangzhou 225125, Jiangsu, China; Jiangsu Institute of Poultry Science, Yangzhou 225125, Jiangsu, China.
G G JiKey Laboratory for Poultry Genetics and Breeding of Jiangsu Province, Yangzhou 225125, Jiangsu, China; Jiangsu Institute of Poultry Science, Yangzhou 225125, Jiangsu, China.
J T ShuKey Laboratory for Poultry Genetics and Breeding of Jiangsu Province, Yangzhou 225125, Jiangsu, China; Jiangsu Institute of Poultry Science, Yangzhou 225125, Jiangsu, China. Electronic address: shujingting@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keel length is a key body size indicator, which has an important impact on the overall growth performance, bone health, and production performance of poultry. In the process of selecting crossed strains for yellow feathered broiler chickens, it is generally necessary to select keel length, but there is little research on keel length development. Therefore, resequencing and GWAS was employed to obtain SNP molecular markers associated with keel length in a specialized Yellow-feathered broiler line. We identified 10 SNPs that were potentially significantly correlated with keel length for the first time located at 9 genes, including ATP7B, CST3, OTOP1, CRMP1, SLC12A1, COPS2, FAM227B, IFT140, APLP2. SNP2 and SNP3 loci were in a strongly linked state (D ' value=1), the other 8 SNP loci were not in a strongly linked state (D 'value<1). The association analysis between single SNP marker and keel length traits showed that TT and CT at SNP1 (rs315701680), GG at SNP2 (rs738740137), AA at SNP3 (rs317223723), AA at SNP4 (rs732443622), GG at SNP5(rs315667756), CC at SNP6 (rs314381113), GG at SNP7 (rs732811384), TT at SNP8 (rs314197610), CC and TC at SNP9 (rs13782000), TT and GT at SNP10 (rs737401141) genotypes were all the dominant genotypes for keel length. The strong linkage between SNP2 and SNP3 resulted in two haplotypes H1 (AG) and H2 (GA), respectively. The H1H1 haplotype (GGAA) produced by SNP2 and SNP3 linkage was the dominant genotype for keel length. The SNP molecular markers and dominant genotypes at SNP1-SNP10 loci identified in this study may be used to improve the accuracy and genetic progress of keel length selection. Meanwhile, candidate genes potentially significantly related to keel length will lay the foundation for genetic selection of keel length and cultivation of high-quality yellow feathered broilers in the future.

Indexed as

ChickensGenome-Wide Association StudyPolymorphism, Single NucleotideAnimalsGenetic MarkersGenetic MarkersBody sizeChickenGWASKeel lengthSNP

Identifiers

PMID41933527
PMCPMC13087754

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.