ArticleCancer imaging : the official publication of the International Cancer Imaging Society2026
Predictive value of real-time shear wave elastography combined with serum thyroglobulin in thyroid cancer.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the diagnostic value of combining real-time shear wave elastography (SWE) with serum thyroglobulin (Tg) in thyroid cancer (TC) and explore its potential for assessing tumor aggressiveness.
methodsThis retrospective study included 124 patients with TC and 62 with benign thyroid lesions (January 2024–August 2025). Malignant cases were classified as invasive (n = 78) or non-invasive (n = 46) based on capsular involvement, vascular invasion, or lymph node metastasis. All patients underwent SWE and Tg testing. SWE parameters—maximum (Emax), mean (Emean), minimum (Emin) Young’s modulus—and Tg levels were compared. ROC analysis assessed diagnostic performance, while Spearman correlation examined relationships between SWE and Tg.
resultsAll malignant cases were papillary thyroid carcinoma. Malignant cases had higher SWE parameters and Tg than benign cases (P < 0.05). Invasive tumors showed higher Emax, Emean, and Tg than non-invasive tumors (P < 0.05). The combined SWE–Tg model AUC for malignancy was 0.844; for aggressiveness, 0.744. Tg correlated positively with SWE parameters (P < 0.001).
conclusionCombining SWE with Tg improved discrimination between TC and benign thyroid nodules in this cohort and may provide auxiliary value for preoperative assessment of invasive features.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.