ReviewOne health outlook2026
Seroprevalence of Q fever among humans and animals in East Africa: a systematic review and meta-analysis.
Review in One health outlook, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Seroprevalence of Q-fever among domestic ruminants, humans and ticks in Ethiopia: A systematic review and meta-analysis.Veterinary and animal science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Q fever is a neglected zoonotic disease caused by Coxiella burnetii with a global distribution. It has a significant public health implication in resource-limited settings. Therefore, this systematic review and meta-analysis were designed to comprehensively analyze the seroprevalence of Q fever in humans and animals in East Africa. Following the PRISMA guidelines and a registered protocol on PROSPERO (CRD420251149865), online searches were conducted in Pubmed, ScienceDirect, Scopus, Web of Science, Google Scholar, and AJOL from October 1–5, 2025, to retrieve articles from the East African countries published within the time frame of January 1, 2000 and September 30, 2025. This systematic review and meta-analysis identified 47 articles reporting Q fever seroprevalence across multiple animal species and human, yielding 94 species-specific datasets for pooled analysis. After heterogeneity assessment, random effects model was used to estimate the pooled Q fever seroprevalence. The estimated pooled seroprevalence was 21.32% (95% CI: [14.58; 28.06]) among humans and 27.55% (95% CI: [22.34; 32.77]) in animals. Trim-and-fill analysis revealed substantial publication bias, reducing pooled seroprevalence from 27.55% to 8.46% in animals and from 21.35% to 6.98% in humans. The seroprevalence in humans was higher in Kenya (26.0%) and Ethiopia (24.7%) than in Sudan (18.0%), Tanzania (14.9%), and Uganda (7.6%). The multivariable meta-regression revealed a significant increasing trend in human Q fever seroprevalence over time, despite marginal non-significance in univariable analysis. Among animals, the seroprevalence was higher in camels (38.9%) and lower in cattle (14.6%), with observed statistically significant difference. This meta-analysis result showed that the seroprevalence of Q fever is high in humans and animals, but it is still neglected in many countries in the East Africa, posing significant impact to human and animal health. Planned preventive measures and control efforts are necessary.
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Registered trials
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