Evidence map›Paper›PMID 41933273›Full record

ArticleMedical physics2026

A simulation study of a novel spiral volumetric modulated arc therapy for enhanced dose delivery efficiency and quality in radiotherapy.

Kuo Li, Wei Zhang, Xingmin Ma, Qichao Zhou, Jian Zhu

Abstract read
In one paragraph

Article in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kuo LiDepartment of Radiation Oncology Physics & Technology, Cancer Hospital of Shandong First Medical University, Jinan, China.
Wei ZhangManteia Technologies Co., Ltd, Xiamen, Fujian, China.
Xingmin MaDepartment of Radiation Oncology Physics & Technology, Cancer Hospital of Shandong First Medical University, Jinan, China.
Qichao ZhouManteia Technologies Co., Ltd, Xiamen, Fujian, China.
Jian ZhuDepartment of Radiation Oncology Physics & Technology, Cancer Hospital of Shandong First Medical University, Jinan, China.

Funding

Key Research and Development Program of Shandong Province 2024CXPT084Major National Science and Technology Project 2024ZD0519901Taishan Scholars Foundation of Shandong Province tstp20250538
6 · The paper itself

Abstract

backgroundConventional volumetric modulated arc therapy (VMAT) is limited by its longitudinal field size for large targets, often requiring multiple isocenters, while Helical Tomotherapy (HT) offers superior longitudinal conformity but suffers from prolonged treatment times due to its narrow fan beam. PURPOSE: This simulation study proposes a novel spiral volumetric modulated arc therapy (SVMAT) technique designed to bridge this gap by synergizing continuous couch movement with dynamic MLC modulation.

methodsThe SVMAT technique was implemented on a model of ring-gantry linac with dual-layer staggered MLC. Its core is a direct aperture optimization algorithm that discretizes the delivery path into finite projections, concurrently optimizing MLC aperture, monitor unit weight, gantry angle, and couch position. A comprehensive dosimetric and efficiency comparison was conducted against state-of-the-art VMAT and HT plans for three clinically challenging scenarios: hippocampal-sparing whole-brain radiotherapy (HS-WBRT), bilateral breast radiotherapy (BBRT), and craniospinal irradiation (CSI), including a pediatric subgroup.

resultsSVMAT demonstrated comparable or superior target coverage and conformity index to VMAT and HT across all cases. Its most significant advantage was in organ-at-risk (OAR) sparing. For HS-WBRT, SVMAT significantly reduced the maximum (D

conclusionsThe SVMAT technique successfully integrates the dynamic delivery of VMAT with the longitudinal integration and single-isocenter capability of HT. By offering enhanced OAR sparing and reduced treatment times, SVMAT represents a significant advancement in radiotherapy, showing immense potential for improving outcomes, especially in vulnerable populations such as pediatric patients.

Indexed as

Radiation DosageRadiotherapy, Intensity-ModulatedHumansOrgans at RiskRadiotherapy DosageRadiotherapy Planning, Computer-Assisteddirect aperture optimizationdosimetric and efficiencypediatric patientsspiral volumetric modulated arc therapy

Identifiers

PMID41933273
PMCPMC13049104

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.