Evidence map›Paper›PMID 41933110›Full record

ArticleEcoHealth2026

First Report of Human Hepatitis B Virus (HBV) in Wild Neotropical Primates.

Jean P Boubli, Hani Rocha El Bizri, Luan F Botelho-Souza, Chrysoula Gubili, Stephen J Martin, Maisa da S Araújo, Tommy C Burch, Mariluce R Messias, Alcione de O Dos Santos, Luiz S Ozaki and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EcoHealth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jean P BoubliSchool of Science, Engineering and the Environment, University of Salford, Salford, Greater Manchester, UK. j.p.boubli@salford.ac.uk.
Hani Rocha El BizriCenter for International Forestry Research (CIFOR), Bogor, Indonesia.
Luan F Botelho-SouzaLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.
Chrysoula GubiliSchool of Science, Engineering and the Environment, University of Salford, Salford, Greater Manchester, UK.
Stephen J MartinSchool of Science, Engineering and the Environment, University of Salford, Salford, Greater Manchester, UK.
Maisa da S AraújoLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.
Tommy C BurchSchool of Science, Engineering and the Environment, University of Salford, Salford, Greater Manchester, UK.
Mariluce R MessiasFundação Universidade Federal de Rondônia, UNIR, Porto Velho, Rondônia, Brazil.
Alcione de O Dos SantosLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.
Luiz S OzakiVirginia Commonwealth University, Richmond, VA, USA.
André V C PereiraLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.
Tony H KatsuragawaLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.
Ana Maísa Passos-SilvaLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.
Luiz H S GilLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.
Izeni P FariasLaboratório de Evolução e Genética Animal, Universidade Federal do Amazonas, Manaus, Amazonas, Brazil.
Juan M V SalcedoLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.
Deusilene VieiraLaboratório de Virologia Molecular, Fundação Oswaldo Cruz Rondônia - FIOCRUZ/RO, Porto Velho, Rondônia, Brazil.

Funding

CNPq SISBIOTA Program 563348/2010-0Fundação Oswaldo Cruz Rondônia (FIOCRUZ/RO), Fiocruz- Rondônia, CT-Amazônia, and CNPq Universal 471196/2011-8
6 · The paper itself

Abstract

Globalization and environmental change are reshaping infectious disease dynamics, including reverse zoonotic transmission from humans to wildlife. We assessed hepatitis B virus (HBV) infection in wild New World primates from two Brazilian Amazon regions: an anthropogenically impacted area in southwestern Amazonia (Rondonia and Mato Grosso states) and a remote, minimally impacted area along the upper Japurá River (Amazonas state). Blood or liver samples from 88 primates representing 28 species were examined for HBV. HBV was detected in 17 of 49 primates (34.7%) from disturbed areas but in none of the 39 primates from the remote site. Human population density significantly predicted infection, and viral genotypes matched locally circulating human HBV strains, supporting human-to-primate spillover driven by deforestation and encroachment.

Indexed as

Animals, WildHepatitis BHepatitis B virusPrimatesAnimalsBrazilGenotypeHumansZoonosesbiodiversitydeforestationemerging infectious diseasesHBVone healthzoonosis

Identifiers

PMID41933110
PMCPMC13582035

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.