Evidence map›Paper›PMID 41932912›Full record

ArticleNature communications2026

Reclassifying lethal heat.

Robert Edwin Rouse, Ramit Debnath, David Andrew Rouse, Will Tebbutt, Bénédicte Dousset, J Scott Hosking, Allan McRobie, Camilo Mora, Emily Shuckburgh

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Robert Edwin RouseDepartment of Computer Science and Technology, University of Cambridge, Cambridge, UK. rer44@cam.ac.uk.ORCID http://orcid.org/0009-0000-4601-0210
Ramit DebnathCollective Intelligence & Design Group and climaTRACES lab, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-0727-5683
David Andrew RouseHome Office Pathologist (Retired), Home Office, London, UK.
Will TebbuttDepartment of Engineering, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-5144-589X
Bénédicte DoussetHawai'i Institute of Geophysics and Planetology, University of Hawai'i at Mānoa, Honolulu, HI, USA.ORCID http://orcid.org/0000-0002-0038-2358
J Scott HoskingBritish Antarctic Survey, Cambridge, UK.ORCID http://orcid.org/0000-0002-3646-3504
Allan McRobieDepartment of Engineering, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-6610-5927
Camilo MoraDepartment of Geography and Environment, University of Hawai'i at Mānoa, Honolulu, HI, USA.ORCID http://orcid.org/0000-0002-7183-960X
Emily ShuckburghDepartment of Computer Science and Technology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-9206-3444

Funding

Bill and Melinda Gates Foundation (Bill & Melinda Gates Foundation) OPP1144RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/R512461/1RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/W002965/1
6 · The paper itself

Abstract

As heatwaves increase in both frequency and intensity globally, the need to develop tools to predict the human impact and develop a more comprehensive understanding of the impact mechanism at a population level is becoming more urgent. Our study provides a taxonomy of heatwaves based on identifying sub-threshold lethal heatwaves through physiological adaptation and vulnerability. We use a classification algorithm applied to a lethal heatwave dataset, comprising 125,411 events where the temperature exceeded the 90th percentile across 140 cities, with combined meteorology and sociodemographic inputs to label these events. The accuracy of our model outperforms classification that relies on wet bulb temperature thresholds with a factor of 11 improvement in imbalanced classification performance. Furthermore, we find that the majority of lethal heatwaves within our dataset occur below high wet bulb temperature thresholds and that accurate predictions for heatwave mortality can be obtained by combining thermo-temporal differentials and population health metrics instead of absolute climatic conditions. We thus propose classifying heatwaves as either: Shock Heatwaves, where aggressive thermo-temporal differentials from a local acclimation point trigger adverse stress effects, particularly among the vulnerable; or Threshold Heatwaves, where high temperature and humidity conditions do exceed the ability to dissipate heat effectively.

Indexed as

Extreme HeatHot TemperatureAcclimatizationAlgorithmsHumansHumidity

Identifiers

PMID41932912
PMCPMC13219605

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.