Evidence map›Paper›PMID 41932885›Full record

ArticleNature communications2026

Hippo signaling differentially regulates distal progenitor subpopulations and their transitional states to construct the mammalian lungs.

Kuan Zhang, Madhuri Basak, Youssef Zaher, Erica Yao, Shao-An Wang, Thin Aung, Pao-Tien Chuang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Kuan Zhang *Cardiovascular Research Institute, University of California, San Francisco, CA, USA.
Madhuri Basak *Cardiovascular Research Institute, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-5161-7321
Youssef Zaher *Cardiovascular Research Institute, University of California, San Francisco, CA, USA.
Erica YaoCardiovascular Research Institute, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-9679-1748
Shao-An WangCardiovascular Research Institute, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-5473-4195
Thin AungCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Pao-Tien ChuangCardiovascular Research Institute, University of California, San Francisco, CA, USA. pao-tien.chuang@ucsf.edu.ORCID http://orcid.org/0000-0002-8961-8653

Funding

Autonomic innervation regulates alveolar formation in developmentR01HL157446 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHUANG, PAO-TIEN · 2022 to 2025
$2.3M
NHLBI NIH HHS R01 HL157446U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL157446
6 · The paper itself

Abstract

Lung size control and cell type specification are key unresolved issues. In this study, we have engineered mosaic patterns of Hippo signaling to reveal the developmental potential of SOX9

Indexed as

LungProtein Serine-Threonine KinasesStem CellsAnimalsCell DifferentiationFemaleGene Expression Regulation, DevelopmentalHippo Signaling PathwayHumansMiceMice, TransgenicSignal TransductionSOX9 Transcription FactorProtein Serine-Threonine KinasesSox9 protein, mouseSOX9 Transcription Factor

Identifiers

PMID41932885
PMCPMC13219436

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.