Evidence map›Paper›PMID 41932815›Full record

Observational studyBMJ open respiratory research2026

Measurement of lung clearance index (LCI

Don S Urquhart, Emily J Taylor, Debbie Miller, Donna Bowens, Ellen Lacey, Mary Abkir, Clare J Saunders, Steve Cunningham, Zoe Louise Saynor, ExACT-CF study group

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMJ open respiratory research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05482048 (ExACT-CF), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05482048 naunknown statusnot on this map

ExACT-CF: Exercise as an Airway Clearance Technique in People With Cystic Fibrosis - A Randomised Pilot Trial

TypeinterventionalSponsorUniversity Hospital Southampton NHS Foundation TrustRan2023 to 2024Enrolled50ConditionsCystic FibrosisArmsExercise as Airway Clearance Therapy (ExACT)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Don S UrquhartDepartment of Child Life and Health, The University of Edinburgh, Edinburgh, UK don.urquhart@nhslothian.scot.nhs.uk.ORCID http://orcid.org/0000-0002-9048-9692
Emily J TaylorDepartment of Child Life and Health, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0009-0004-9541-785X
Debbie MillerAdult Cystic Fibrosis Unit, Western General Hospital, Edinburgh, UK.
Donna BowensUniversity Hospitals Southampton NHS Foundation Trust, Southampton, UK.
Ellen LaceyUniversity Hospitals Southampton NHS Foundation Trust, Southampton, UK.
Mary AbkirNational Heart and Lung Institute, Imperial College London, London, UK.
Clare J SaundersNational Heart and Lung Institute, Imperial College London, London, UK.
Steve CunninghamDepartment of Child Life and Health, The University of Edinburgh, Edinburgh, UK.
Zoe Louise SaynorUniversity Hospitals Southampton NHS Foundation Trust, Southampton, UK.ORCID http://orcid.org/0000-0003-0674-8477
ExACT-CF study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung clearance index (LCI

methodsN

results49 participants (21 female; age: 10-55 years, FEV

conclusionsN TRIAL REGISTRATION NUMBER: NCT05482048.

Indexed as

Cystic FibrosisLungNitrogenRespiratory Function TestsAdolescentAdultBreath TestsChildFeasibility StudiesFemaleForced Expiratory VolumeHumansMaleMiddle AgedRandomized Controlled Trials as TopicYoung AdultNitrogenCystic FibrosisLung PhysiologyRespiratory Measurement

Identifiers

PMID41932815
PMCPMC13052781

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.