Evidence map›Paper›PMID 41931868›Full record

ArticlePoultry science2026

Hens and roosters of two distinct lines differ in immune cell profiles.

Tanja Hofmann, Volker Stefanski, Werner Bessei, Sonja Schmucker

Abstract read
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tanja HofmannInstitute of Animal Science, University of Hohenheim, Garbenstr. 17, 70599 Stuttgart, Germany. Electronic address: tanja.hofmann@uni-hohenheim.de.
Volker StefanskiInstitute of Animal Science, University of Hohenheim, Garbenstr. 17, 70599 Stuttgart, Germany.
Werner BesseiInstitute of Animal Science, University of Hohenheim, Garbenstr. 17, 70599 Stuttgart, Germany.
Sonja SchmuckerInstitute of Animal Science, University of Hohenheim, Garbenstr. 17, 70599 Stuttgart, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sexual dimorphism in immune function influences disease susceptibility, yet sex-specific immune characteristics in chickens remain poorly understood, particularly across genetically divergent lines. This study investigated sex- and line-dependent differences in the peripheral and lymphatic immune system in lines selected for high and low feather pecking. Immune cell subsets were quantified in blood, spleen and cecal tonsils, and functional immune parameters were analyzed by measuring plasma antibody concentration and mitogen-induced lymphocyte proliferation capacity. Distinct immunological differences were observed between roosters and hens, as well as between lines, with several effects being tissue- and sex-specific. The higher overall numbers of immune cells observed in the spleen of roosters were primarily attributable to their larger organ mass, whereas in the cecal tonsils this was mainly due to a higher cell density. Roosters had fewer peripheral B cells, lower antibody concentrations and B lymphocyte proliferation capacity, along with fewer CD4

Indexed as

ChickensAnimalsCell ProliferationFeathersFemaleMaleSpleenChickenGenetic lineImmune systemSexual dimorphism

Identifiers

PMID41931868
PMCPMC13087782

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.