Evidence map›Paper›PMID 41931607›Full record

ArticleScience advances2026

Structural insights into the mechanism underpinning iron piracy in pathogenic

Shubham Dubey, Julie Stoudenmire, Gabriel Bury, Lixinhao Yang, Zixing Fan, Peihang Li, Gauree Wadhwa, Yulia Pushkar, James C Gumbart, Cynthia Nau Cornelissen and 1 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shubham DubeyMarkey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-0281-9306
Julie StoudenmireCenter for Translational Immunology, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.ORCID 0000-0002-7269-1133
Gabriel BuryDepartment of Physics and Astronomy, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0001-6555-9954
Lixinhao YangSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Zixing FanInterdisciplinary Bioengineering Graduate Program, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Peihang LiMarkey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0009-0002-8337-929X
Gauree WadhwaCenter for Translational Immunology, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.ORCID 0009-0008-3827-488X
Yulia PushkarDepartment of Physics and Astronomy, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0001-7949-6472
James C GumbartSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.ORCID 0000-0002-1510-7842
Cynthia Nau CornelissenCenter for Translational Immunology, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
Nicholas NoinajMarkey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0001-6361-2336

Funding

Neisseria gonorrhoeae metal transporters that subvert nutritional immunityR01AI127793 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CYNTHIA N CORNELISSEN, Alison K Criss · 2017 to 2026
$6.8M
Elucidating the mechanisms of protein secretion across the outer membrane by bacterial autotransportersR01GM148586 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI James C. Gumbart · 2023 to 2026
$1.8M
NIAID NIH HHS R01 AI127793NIGMS NIH HHS R01 GM148586
6 · The paper itself

Abstract

The pathogenesis of

Indexed as

Bacterial ProteinsIronNeisseriaNeisseria gonorrhoeaeTransferrin-Binding Protein ATransferrin-Binding Protein BCryoelectron MicroscopyElectron Spin Resonance SpectroscopyModels, MolecularMolecular Dynamics SimulationProtein BindingProtein ConformationTransferrinBacterial ProteinsIronTransferrinTransferrin-Binding Protein ATransferrin-Binding Protein B

Identifiers

PMID41931607
PMCPMC13048262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.