Evidence map›Paper›PMID 41931445›Full record

ArticleCardiorenal medicine2026

Intra-Dialytic Hypotension and the VExUS Assessment in Hospitalized Patients: A Prospective Cohort Study.

Rose Joyal, Josiane Proulx, Michel Gouin, Karel Huard, Lawrence Ledoux-Hutchinson, Sophie Gilbert, Emmanuel Charbonney, André Denault, William Beaubien-Souligny

Abstract read
In one paragraph

Article in Cardiorenal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rose JoyalFaculty of Medicine, University of Montreal, Montreal, Québec, Canada.
Josiane ProulxFaculty of Medicine, University of Montreal, Montreal, Québec, Canada.
Michel GouinFaculty of Medicine, University of Montreal, Montreal, Québec, Canada.
Karel HuardFaculty of Medicine, University of Montreal, Montreal, Québec, Canada.
Lawrence Ledoux-HutchinsonFaculty of Medicine, University of Montreal, Montreal, Québec, Canada.
Sophie GilbertFaculty of Medicine, University of Montreal, Montreal, Québec, Canada.
Emmanuel CharbonneyService of Intensive Care Unit, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Québec, Canada.
André DenaultDepartment of Anesthesiology, Montréal Heart Institute, Montreal, Québec, Canada.
William Beaubien-SoulignyService of Nephrology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Québec, Canada, william.beaubien-souligny.med@ssss.gouv.qc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPredicting tolerance to fluid removal is particularly challenging in hospitalized, acutely ill patients. This study evaluated the association between the Venous Excess Ultrasound (VExUS) and IDHE in hospitalized patients.

methodsThis single-center prospective cohort included hospitalized between 2022 and 2024 receiving hemodialysis. Ultrasound of the inferior vena cava (IVC), hepatic, portal, and femoral veins was performed. Patients were classified into four VExUS grades (0 to 3) based on IVC dimensions and venous Doppler waveforms. Follow-up at 3 months was conducted to evaluate outcomes across the different groups.

resultsThe cohort consisted of 93 patients. VExUS grading showed grade 0 in 52 patients (55.9%), grade 1 in 22 patients (23.7%), grade 2 in 11 patients (11.8%), and grade 3 in 8 patients (8.6%). The incidence of IDHE was tended to be higher in VExUS grade 0 (40.4%) and VExUS grade 3 (50.0%) patients compared with VExUS grade 1 (18.2%) or 2 (18.2%) (p = 0.145). The cumulative duration of hypotension (sBP <90 mm Hg) differed between VExUS groups (p = 0.03), with VExUS grade 3 patients experiencing longer median duration of hypotension compared to participants with a VExUS grade 1 (16.4 [0; 47.5] vs. 0 [0; 0] min, p = 0.04).

conclusionOur findings showed a trend toward more frequent IDHE in both VExUS grade 0 and grade 3, with grade 3 patients experiencing a significantly longer cumulative duration of hypotension. High VExUS scores may identify patients at increased risk of hypotension due to impaired hemodynamic adaptability.

Indexed as

HypotensionRenal DialysisVena Cava, InferiorAgedFemaleFemoral VeinHepatic VeinsHospitalizationHumansIncidenceMaleMiddle AgedProspective StudiesUltrasonography, DopplerFluid balanceHemodialysisHypotensionUltrafiltrationVenous DopplerVExUS

Identifiers

PMID41931445
PMCPMC13268610

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.