Ross Procedure After Valve-Sparing Root Replacement With Marfan Syndrome.

Hiroaki Osada, Kenji Minatoya, Fumie Takai, Takahide Takeda, Takehiko Matsuo, Yutaka Okita

Abstract readCase Reports

In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Hiroaki OsadaDepartment of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Kenji MinatoyaDepartment of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address: minatoya@kuhp.kyoto-u.ac.jp.

Fumie TakaiDepartment of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Takahide TakedaDepartment of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Takehiko MatsuoDepartment of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Yutaka OkitaCardio-Aortic Center, Takatsuki General Hospital, Takatsuki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Ross procedure is one of the optimal surgical options for aortic valve pathologies in relatively young patients. However, its application in patients with Marfan syndrome (MFS) is not only debatable but may even be considered a contraindication. CASE SUMMARY: A 31-year-old woman with MFS had undergone valve-sparing root replacement 2.5 years earlier and now presented for treatment of severe aortic insufficiency (AI). A Ross procedure with stabilization of the aortic root was performed. Two years after the procedure, mild AI was observed; however, the patient was asymptomatic, and left ventricular function was preserved. DISCUSSION: Although the latest expert consensus concludes that Ross procedures should be avoided in patients with MFS, it may be premature to rule out the procedure solely because of the potential for autograft dilation. TAKE-HOME MESSAGES: For patients with MFS, while the Ross procedure may not necessarily be considered a contraindication, careful consideration of its indication is necessary. If surgery is performed, modifications and meticulous follow-up are required.

Indexed as

aortic insufficiencyMarfan syndromeRoss procedurevalve-sparing root replacement

Identifiers

PMID41931095

DOI10.1016/j.jaccas.2026.107759

PMCPMC13184883

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