Evidence map›Paper›PMID 41931094›Full record

ArticleJACC. Case reports2026

Differentiating LAA Thrombus From Spontaneous Echo Contrast for Safe LAA Occlusion.

Ashraf Sliem, Steven Douedi, Chunheung Chen, Daniel Ice

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ashraf SliemInternal Medicine Department, Southern Ocean Medical Center, Manahawkin, New Jersey, USA. Electronic address: sliem.amas@gmail.com.
Steven DouediCardiology Department, Deborah Heart and Lung Center, Browns Mills, New Jersey, USA.
Chunheung ChenCardiology Department, Deborah Heart and Lung Center, Browns Mills, New Jersey, USA.
Daniel IceCardiology Department, Deborah Heart and Lung Center, Browns Mills, New Jersey, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left atrial appendage (LAA) occlusion is a valuable therapeutic option for stroke prevention in patients with atrial fibrillation who have contraindication to long-term anticoagulation. However, the presence of LAA thrombus is a contraindication to device implantation. Differentiating a true thrombus from spontaneous echo contrast or "sludge" on transesophageal echocardiography is both challenging and crucial for procedural safety. We present a series of cases using adjunctive modalities that allowed safe LAA occluder deployment.

Indexed as

anticoagulationatrial fibrillationcontrast agentechocardiographyimaginginotropes

Identifiers

PMID41931094
PMCPMC13184869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.