ArticleMedComm2026
Neuroprotective Effect of Remote Ischemic Conditioning on Patients Undergoing Intravenous Thrombolysis: A Randomized Controlled Trial.
Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05598658 (Effect of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients After Intravenous Thrombolysis), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients After Intravenous Thrombolysis (RICCH-IVT)
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravenous thrombolysis (IVT) is the treatment with the highest level of evidence for acute ischemic stroke, but about half of patients fail to achieve a favorable prognosis. This study (NCT05598658) proposed a treatment strategy of adjunctive two sessions of remote ischemic conditioning (RIC) within 24 h after IVT, and evaluated the effects through cerebral autoregulation (CA) and brain-injury biomarkers. Patients were randomized (1:1) to the RIC or sham-RIC groups, which received 200 and 60 mmHg RIC, respectively, at 6 and 18-24 h after IVT. CA was assessed at 2 and 7 days after IVT and serum brain-injury biomarkers were evaluated at 24 h after IVT. The primary outcome was CA at 2 days after IVT. A total of 100 patients were randomized to the RIC or sham-RIC group. Ipsilateral CA was significantly higher in the RIC group than in the sham-RIC group at 2 days (β: 14.970 [95% confidence interval, 7.741-22.199;
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