ArticleTherapeutic advances in urology
Assessment of lower urinary tract symptoms and health-related quality of life in patients undergoing ureteral rest prior to ureteral reconstruction.
Article in Therapeutic advances in urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Ureteral rest refers to the removal of hardware across a ureteral stricture, allowing for stricture maturation and stabilization, before ureteral reconstruction. Objectives: We aimed to assess the potential impact of ureteral rest on lower urinary tract symptoms (LUTS) and health-related quality of life (HRQOL) in patients undergoing ureteral rest. Design: Prospective, longitudinal, self-controlled study. Methods: We included patients undergoing ureteral reconstruction between April 2022 and April 2025. We defined ureteral rest as replacing an indwelling double-J stent (DJS) with a percutaneous nephrostomy tube (PCN) prior to ureteral reconstruction. Primary outcomes were patient-reported LUTS (via International Prostate Symptom Score) and HRQOL (via Patient-Reported Outcomes Measurement Information System 29 v2.0). The secondary outcome was the incidence of urinary tract infections (UTIs). Questionnaires were completed prior to initiating ureteral rest (with a DJS) and after at least 3 weeks of ureteral rest (with a PCN). Continuous and categorical variables were compared using paired t-tests and chi-squared tests, respectively. Results: Thirty-five patients met our study's inclusion criteria. With regard to LUTS, patients undergoing ureteral rest were found to have reduced urinary frequency ( Conclusion: Patients undergoing ureteral rest prior to ureteral reconstruction may experience improvements in LUTS without compromising HRQOL outcomes or increasing the risk of UTIs.
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