Evidence map›Paper›PMID 41930267›Full record

ArticleOrganic process research & development2025

Coamorphous Solid Dispersion of a Soluble Epoxide Hydrolase Inhibitor t-TUCB with Amino Acid l-Arginine.

Sung Hee Hwang, Karen M Wagner, Jun Yang, Christophe Morisseau, Debin Wan, James C Fettinger, Marilyn M Olmstead, Bruce D Hammock

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic process research & development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sung Hee HwangDepartment of Entomology & Nematology, and UC Davis Comprehensive Cancer Center, University of California, One Shields Avenue, Davis, California 95616-8584.
Karen M WagnerDepartment of Entomology & Nematology, and UC Davis Comprehensive Cancer Center, University of California, One Shields Avenue, Davis, California 95616-8584.
Jun YangDepartment of Entomology & Nematology, and UC Davis Comprehensive Cancer Center, University of California, One Shields Avenue, Davis, California 95616-8584.
Christophe MorisseauDepartment of Entomology & Nematology, and UC Davis Comprehensive Cancer Center, University of California, One Shields Avenue, Davis, California 95616-8584.
Debin WanDepartment of Entomology & Nematology, and UC Davis Comprehensive Cancer Center, University of California, One Shields Avenue, Davis, California 95616-8584.
James C FettingerDepartment of Chemistry, University of California, One Shields Avenue, Davis, California 95616-8584.
Marilyn M OlmsteadDepartment of Chemistry, University of California, One Shields Avenue, Davis, California 95616-8584.
Bruce D HammockDepartment of Entomology & Nematology, and UC Davis Comprehensive Cancer Center, University of California, One Shields Avenue, Davis, California 95616-8584.

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1987 to 2021
$50.1M
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate IntoxicationU54NS127758 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Amy R. Brooks-Kayal, Pamela J Lein · 2022 to 2026
$17.2M
Supplement for bioactive lipids as effectors and indicators of the deleterious effects of human healthR35ES030443 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MORISSEAU, CHRISTOPHE HP · 2019 to 2025
$5.8M
NIEHS NIH HHS P42 ES004699NIEHS NIH HHS R35 ES030443NINDS NIH HHS U54 NS127758
6 · The paper itself

Abstract

Inhibitors of soluble epoxide hydrolase (sEHIs) have been of interest for treating various diseases in humans and animals. Therefore, various sEHIs have been investigated in several clinical trials. Here, we report the development of a co-amorphous solid dispersion of an sEHI

Indexed as

aggregationco-amorphous solid dispersioncolloidal particlesinflammatory painL-argininepolymorphsoluble epoxide hydrolase inhibitort-TUCB

Identifiers

PMID41930267
PMCPMC13042890

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.