Evidence map›Paper›PMID 41930194›Full record

ArticleFrontiers in oncology2026

Precision distance control in ultrasound-guided coaxial needle biopsy for small liver cancer: improving safety and diagnostic accuracy yield.

Yaqi Zhang, Qian Huang, Lilin Zhao, Ting Zhang

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Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yaqi ZhangDepartment of Ultrasound, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, China.
Qian HuangDepartment of Ultrasound, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, China.
Lilin ZhaoDepartment of Ultrasound, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, China.
Ting ZhangDepartment of Ultrasound, The Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The diagnostic yield of percutaneous biopsy for small liver cancer is affected by lesion size and location. This study utilizes small components with a coaxial cannula to enables precise control over specimen length, aiming to evaluate the safety and clinical applicability of ultrasound-guided coaxial needle biopsy. Methods: In the coaxial group, the biopsy gun's position relative to the coaxial cannula was adjusted, and small components were used to control specimen length. Thrombin (1-2 KU) was injected along the needle tract post-procedure. In the non-coaxial group, multiple needle insertions targeted the lesion edge. Complications and pathology results were recorded to assess clinical efficacy. Results: A retrospective analysis of 744 patients from Jiangsu Provincial Cancer Hospital showed a higher pathological detection rate in the coaxial group (95.6%, 198/207) than in the non-coaxial group (89%, 478/537). Intraoperative bleeding was more easily detected in the coaxial group, allowing timely intervention. Pain was reported in 15% (31/207) versus 30% (161/537), respectively. No needle tract implantation occurred in either group. Conclusion: Ultrasound-guided coaxial needle biopsy for small liver cancer (≤2 cm) significantly improves diagnostic accuracy (P = 0.005), reduces procedure complexity and complications, and enhances patient outcomes, demonstrating excellent safety and clinical value.

Indexed as

coaxial needleprecision distance controlprocedure - related complicationssmall componentsmall liver cancer

Identifiers

PMID41930194
PMCPMC13038430

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