ArticleFrontiers in medicine2026
A retrospective cohort study in China: association between
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Introduction: Materials and methods: We conducted a retrospective study of 146 RA patients on TGs, 62 on MTX, and 54 on TGs + MTX. Serum albumin was measured before and after treatment. Logistic regression analysis was used to identify factors associated with post-treatment hypoalbuminemia. Results: Serum albumin levels did not differ significantly among the TGs, MTX, and TGs + MTX groups at baseline. Following treatment, the TGs and TGs + MTX groups exhibited significant decreases in mean serum albumin. In contrast, the MTX group showed stable albumin levels. Consequently, the incidence of hypoalbuminemia increased significantly after treatment with TGs (from 3.4 to 26.0%, Conclusion: Treatment with TGs, either alone or in combination with MTX, was associated with the development of hypoalbuminemia in patients with RA. This effect was significantly associated with advanced age, suggesting a need for closer monitoring in this vulnerable population.
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