ArticleCureus2026
Burden of Latent Tuberculosis Infection (LTBI) Among Patients Attending a Tertiary Care Hospital in Eastern India: A Descriptive Study.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionLatent tuberculosis infection (LTBI) is still neglected and acts as a barrier to the tuberculosis (TB) elimination goal of the National Tuberculosis Elimination Programme (NTEP) by 2025 sustaining TB transmission, particularly in high-burden countries like India. Unlike active TB, which is symptomatic and contagious, LTBI is non-infectious and asymptomatic. However, in LTBI,
resultsLTBI was detected in 56 patients, yielding a prevalence of 23.7% (56/236). Most LTBI-positive individuals were male and aged 30-45 years. A high proportion had underlying autoimmune diseases, while 19.6% (11/56) had no identifiable risk factors which refers to the absence of documented traditional exposures (e.g., household contact), comorbid condition, or clinical indication for screening. DISCUSSION: The substantial LTBI burden, particularly among immunocompromised individuals, highlights gaps in targeted screening strategies. Our study identified the proportion of LTBI among patients attending a tertiary care hospital in Eastern India to be 23.7% which is lower than the global average of about 33%. The relatively younger and healthy population participating in the study can also contribute to the low LTBI frequency, as older individuals usually have a high cumulative risk of
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