Evidence map›Paper›PMID 41929704›Full record

ArticleFrontiers in neuroscience2026

Perception of brain-computer interface implantation surgery for motor, sensory, and autonomic restoration in spinal cord injury and stroke.

Derrick Lin, Tracie Tran, Shravan Thaploo, Jose Gabrielle E Matias, Joy E Pixley, Zoran Nenadic, An H Do

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Derrick LinDepartment of Neurology, University of California, Irvine, Irvine, CA, United States.
Tracie TranDepartment of Neurology, University of California, Irvine, Irvine, CA, United States.
Shravan ThaplooDepartment of Biomedical Engineering, University of California, Irvine, Irvine, CA, United States.
Jose Gabrielle E MatiasDepartment of Neurology, University of California, Irvine, Irvine, CA, United States.
Joy E PixleyIndependent Researcher (formerly at University of California, Irvine), Irvine, CA, United States.
Zoran NenadicDepartment of Biomedical Engineering, University of California, Irvine, Irvine, CA, United States.
An H DoDepartment of Neurology, University of California, Irvine, Irvine, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Stroke and spinal cord injury (SCI) can profoundly diminish quality of life across physical and psychosocial domains, with motor and sensory deficits often persisting despite current therapies. Invasive brain-computer interface (BCI) systems, particularly electrocorticography (ECoG)-based approaches, offer a potential means to bypass neural injury and restore function. To inform development and deployment, it is critical to understand candidate users' willingness to adopt such technology and how that willingness relates to their functional goals and rehabilitation priorities. Methods: We conducted a survey assessing receptiveness to surgical implantation of ECoG grids for BCI use and eliciting participants' rehabilitative goals and perceived priorities across motor and sensory domains. We examined associations between willingness to undergo implantation and (1) the level of functional recovery hypothetically offered, (2) stated rehabilitative priorities, and (3) self-reported disability. Results: We surveyed 71 participants: stroke ( Discussion: These findings indicate a strong interest in invasive BCIs even when only basic functions may be restored, independent of disability severity or stated priorities. This suggests that first-generation commercial invasive BCIs with limited functionality may still find receptive users. However, stated interest may not translate to informed surgical consent in real-world contexts, thereby highlighting the risk of overly optimistic expectations. Hence, robust, transparent consent frameworks and balanced communication are essential as invasive BCIs move toward clinical deployment.

Indexed as

brain-computer interface (BCI)electrocorticography (ECoG)functional restorationneuroethicsspinal cord injury (SCI)stroke rehabilitationsurgical willingnesssurvey

Identifiers

PMID41929704
PMCPMC13039023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.