ArticleFrontiers in neurology
Modified Framingham stroke risk profile and related research on uric acid in individuals aged over 65 years in the Yangtze River Delta region, China.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: With socioeconomic advancement stroke has garnered extensive public attention. Aims: This study aimed to assess the 10-year risk of stroke among individuals aged over 65 years within a community utilizing the modified Framingham Stroke Profile (FSP). Additionally, the characteristics of high-risk factors for stroke and their associations with peripheral blood uric acid levels (UA) were explored. Methods: A cross-sectional stratified survey method was employed, adhering to the principles of stratified sampling. Between February and October 2020, residents from seven community committees in the Suzhou High-tech Zone were selected to participate in questionnaire surveys and undergo blood biomarker testing to evaluate the 10-year stroke risk of stroke using the modified FSP. Results: According to the population-based modified FSP risk assessment, 823 individuals (51.0%) were classified as low risk, 703 individuals (43.6%) as medium risk, and 87 individuals (5.4%) as high risk. Peripheral blood uric acid levels were positively correlated with the 10-year stroke risk score ( Conclusion: The stroke risk profile in this region warrants serious consideration. Elevated levels of uric acid (UA) are associated with increased modified FSP risk. Consequently, peripheral uric acid may serve as a limited indicator for discriminating medium-to-high modified FSP risk.
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