Evidence map›Paper›PMID 41929578›Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2026

Changing case definition: An analysis of its impact on Lyme disease surveillance in Nova Scotia.

Kelachi Nsitem, Jennifer Cram, Aini Khan, Colleen Ryan, Todd Hatchette, Shelley Deeks, Linda Passerini, Molly Trecker, Kathryn McIsaac

Abstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kelachi NsitemDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.
Jennifer CramDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.
Aini KhanDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.
Colleen RyanDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.
Todd HatchetteDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.
Shelley DeeksDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.
Linda PasseriniDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.
Molly TreckerDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.
Kathryn McIsaacDepartment of Health and Wellness, Government of Nova Scotia, Halifax, NS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nova Scotia has experienced a growing number of Lyme disease (LD) cases since 2002. From 2009 to 2022, Nova Scotia adopted a LD case definition that aligned with the Public Health Agency of Canada's definition. On January 1, 2023, Nova Scotia transitioned to a LD definition that relies on laboratory evidence alone. Objectives: To describe and compare historic trends in confirmed LD case counts and incidence under the former and current LD case definitions between 2018 and 2023 and assess the impact of the case definition change on LD surveillance. Methods: Confirmed LD cases were extracted from Nova Scotia's Electronic Public Health Information System, software Panorama, according to the former case definition for the years 2018-2022 and the current case definition for the years 2019-2023. As the 2018 laboratory data in Panorama was incomplete, raw data for 2018 were obtained from Nova Scotia's Provincial Public Health Laboratory Network. Confirmed case counts and incidence rates per 100,000 population were calculated by year, sex, age group and geographic zone, under both case definitions. Seasonality was determined by the reporting date of the case. Results: From 2018-2022, the current case definition identified 4,238 cases, a substantial increase of 2,493 cases over the 1,745 reported by the former case definition, with an additional 2,058 cases in 2023 under the current case definition. This led to a clear upward trend in confirmed incidence rates with the current case definition, unlike the variable pattern seen with the former case definition. Males and individuals aged 5-14, 40-59, and ≥60 years experienced consistently higher sex and age-specific rates under both case definitions. The Western Zone consistently reported the highest incidence rates. Seasonally, both case definitions showed reporting peaks from June to September, with the peak occurring two-week later peak with the current case definition. Conclusion: When the current LD case definition was applied to historic surveillance data, past rates of confirmed LD increased suggesting under-reporting of clinical presentation of LD to public health in high incidence jurisdictions.

Indexed as

Lyme diseaseNova Scotiasurveillancetick-borne disease

Identifiers

PMID41929578
PMCPMC13042998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.