Evidence map›Paper›PMID 41929450›Full record

ReviewFrontiers in cellular and infection microbiology2026

The fungal stronghold: biofilms in hemodialysis catheters, diagnostic pitfalls, and the challenge of catheter salvage.

Jie Shi, Naiying Lan, Fanzhou Zeng, Nanmei Liu, Cheng Xue, Bo Yang

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie ShiDepartment of Disease Control and Prevention, Naval Medical Center of People's Liberation Army (PLA), Naval Medical University, Shanghai, China.
Naiying LanDepartment of Nephrology, Naval Medical Center of People's Liberation Army (PLA), Naval Medical University, Shanghai, China.
Fanzhou ZengDepartment of Nephrology, Naval Medical Center of People's Liberation Army (PLA), Naval Medical University, Shanghai, China.
Nanmei LiuDepartment of Nephrology, Naval Medical Center of People's Liberation Army (PLA), Naval Medical University, Shanghai, China.
Cheng XueDepartment of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA, United States.
Bo YangDepartment of Nephrology, Naval Medical Center of People's Liberation Army (PLA), Naval Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of fungal catheter-related bloodstream infections (CRBSIs) in the hemodialysis population represents a critical collision between rigorous infectious disease guidelines and the grim clinical reality of vascular access exhaustion. While guidelines from the IDSA and KDIGO unequivocally recommend immediate catheter removal to prevent metastatic complications, nephrologists are frequently confronted with patients for whom the current catheter represents the last viable lifeline. This review provides a comprehensive analysis of the "catheter salvage" dilemma, moving beyond superficial treatment algorithms to explore the molecular and structural mechanisms that make fungal biofilms a formidable adversary. We dissect the pathogenesis of

Indexed as

BiofilmsCandidaCatheter-Related InfectionsCathetersRenal DialysisAntifungal AgentsHumansAntifungal Agentsantifungal lock therapycatheter-related bloodstream infectioncatheter salvagefungal biofilmhemodialysis

Identifiers

PMID41929450
PMCPMC13038993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.