Evidence map›Paper›PMID 41929449›Full record

ArticleFrontiers in cellular and infection microbiology2026

Effect of periodontal therapy on the oral microbiome and lung function: an intervention study.

Anders Røsland, Hesham Amin, Stein Atle Lie, Andrei Malinovschi, Dagmar F Bunæs, Randi J Bertelsen

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anders RøslandDepartment of Clinical Dentistry, Section of Periodontics, University Of Bergen, Bergen, Norway.
Hesham AminDepartment of Clinical Science, University Of Bergen, Bergen, Norway.
Stein Atle LieDepartment of Clinical Dentistry, Centre for Translational Oral Research (TOR), University of Bergen, Bergen, Norway.
Andrei MalinovschiDepartment of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
Dagmar F BunæsDepartment of Clinical Dentistry, Section of Periodontics, University Of Bergen, Bergen, Norway.
Randi J BertelsenDepartment of Clinical Science, University Of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The oral cavity harbors over 700 bacterial species, and disruption of this balance can lead to periodontitis, which has been linked to systemic conditions including respiratory disease. Methods: In this longitudinal clinical trial, 57 never-smoking adults with stage I-II periodontitis underwent full-mouth periodontal disinfection. Airway resistance and subgingival plaque sampling (analyzed by shotgun metagenomics) was measured at baseline and six weeks after therapy. Results: Periodontal treatment significantly improved clinical periodontal parameters, and was associated with reductions in airway resistance. Microbiome analysis showed a shift from periodontitis-associated taxa, including Discussion: Together, findings suggest that periodontal therapy promotes a healthier oral microbiome and is associated with improved lung function in non-smokers with no prior lung disease.

Indexed as

LungMicrobiotaMouthPeriodontitisAdultBacteriaDental PlaqueFemaleHumansLongitudinal StudiesMaleMetagenomicsMiddle AgedRespiratory Function Testsairway resistanceforced oscillation techniqueoral-lung axisperiodontal therapyperiodontitisplaque subgingival microbiomeshotgun metagenomics

Identifiers

PMID41929449
PMCPMC13038898

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.