Evidence map›Paper›PMID 41929438›Full record

ArticleEuropean heart journal. Case reports2026

Successful mechanical thrombectomy of a large venous graft thrombus burden using a novel device in an unusual way: a case report.

Nikolaus Löffelhardt, Christian Marc Valina, Alexander Kille, Dirk Westermann, Philipp Breitbart

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nikolaus LöffelhardtDepartment of Cardiology and Angiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Südring 15, Bad Krozingen 79189, Germany.
Christian Marc ValinaDepartment of Cardiology and Angiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Südring 15, Bad Krozingen 79189, Germany.
Alexander KilleDepartment of Cardiology and Angiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Südring 15, Bad Krozingen 79189, Germany.
Dirk WestermannDepartment of Cardiology and Angiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Südring 15, Bad Krozingen 79189, Germany.ORCID https://orcid.org/0000-0002-7542-1956
Philipp BreitbartDepartment of Cardiology and Angiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Südring 15, Bad Krozingen 79189, Germany.ORCID https://orcid.org/0000-0002-7390-5287

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mechanical thrombectomy (mTE) is an established standard of care for selected patients with acute ischaemic stroke. However, in the cardiac equivalent-acute coronary syndrome-current guidelines do not recommend mTE. This is primarily based on trials showing no mortality benefit from routine thrombus aspiration, along with an increased risk of stroke. Case summary: A 76-year-old male with known three-vessel coronary artery disease and a history of coronary artery bypass grafting presented to our emergency department with a non-ST-elevation myocardial infarction. Angiography revealed a subacute occlusion of the saphenous vein graft to the posterior descending artery. An initial attempt at percutaneous coronary intervention of the native right coronary artery was unsuccessful due to severe calcification. Following successful recanalization of the vein graft, a high thrombus burden persisted despite manual aspiration and tirofiban bolus with continuous infusion, as confirmed by repeat angiography at the next day. Consequently, we performed mTE using a stent retriever system, achieving complete thrombus removal. This was followed by stent implantation in the vein graft, with final angiography demonstrating full restoration of distal perfusion. This case highlights the value of mTE as a bailout strategy in cases with a substantial thrombus burden, particularly in vein grafts, and underscores the potential of a stepwise approach starting with aspiration and escalating to mTE if required. Discussion: This case illustrates that in selected cases of myocardial infarction with a substantial thrombus burden, mTE may help achieve TIMI-III flow and reduce the risk of distal embolization. Moreover, it demonstrates the feasibility of delivering a stent retriever through an aspiration catheter, thereby enabling a less invasive, resource-efficient, and potentially safer procedural strategy without the need for a dedicated microcatheter.

Indexed as

Acute myocardial infarctionCase reportLarge thrombus burdenMechanical thrombectomyVenous graft

Identifiers

PMID41929438
PMCPMC13042249

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.