Evidence map›Paper›PMID 41929369›Full record

ArticleFrontiers in psychiatry2026

Therapeutic exercise is associated with dose-dependent reductions in acute anxiety across psychiatric diagnoses.

Sandra Perunova, Inese Kokina, Indrikis A Krams

Abstract read
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Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Sandra PerunovaDaugavpils Psychoneurological Hospital, Daugavpils, Latvia.
Inese KokinaDepartment of Technology, Institute of Life Sciences and Technology, Daugavpils, Latvia.
Indrikis A KramsDepartment of Biodiversity, Institute of Life Sciences and Technology, Daugavpils, Latvia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute anxiety is common across psychiatric disorders and may interfere with treatment engagement. Although physical activity is known to improve long-term mental health outcomes, less is known about its immediate associations with anxiety reduction in real-world psychiatric settings. This study examined whether participation in therapeutic exercise sessions is associated with short-term changes in self-reported anxiety and whether greater program participation is related to larger reductions. Materials and methods: We analyzed data from 179 adult psychiatric patients participating in a structured therapeutic exercise program including (i) 30-45-minute walking sessions, (ii) stretching/yoga-like sessions, and (iii) 5-10-minute diaphragmatic breathing exercises. Self-reported anxiety was assessed using the GAD-7 questionnaire administered immediately before and immediately after exercise sessions. Non-parametric tests evaluated pre-post changes, and Spearman correlations assessed associations between session counts and anxiety change. Results: Self-reported anxiety scores were significantly lower after exercise sessions (median pre = 3; median post = 2; Wilcoxon P < 0.001). Improvement was observed in 81% of patients. Anxiety reductions did not differ significantly by sex, diagnosis, or age. Greater participation in walking, stretching/yoga, and breathing sessions was associated with larger decreases in anxiety (Spearman ρ = -0.63 to -0.66, all P < 0.001). Because exercise modalities were highly intercorrelated, these findings likely reflect overall program engagement rather than modality-specific effects. Discussion: In this observational clinical sample, participation in exercise sessions was consistently associated with large, rapid short-term reductions in self-reported anxiety across diagnostic categories. The observed dose-response associations suggest that greater engagement may be linked to larger improvements. However, the absence of a control group and the use of a symptom questionnaire in a session-based format limit causal inference. Controlled trials are needed to determine the extent to which exercise itself, expectancy effects, or contextual factors contribute to these improvements.

Indexed as

aerobic walkinganxiety reductiondiaphragmatic breathingGAD-7 assessmentpsychiatric patientsstretching and relaxationtherapeutic exercise

Identifiers

PMID41929369
PMCPMC13038590

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.