Evidence map›Paper›PMID 41929357›Full record

ArticleInternational journal of biomaterials2026

Therapeutic Effect of Eugenol-Loaded Chitosan Nanoparticles Against

Mohammad Javad Tahmasebi, Mahmoud Osanloo, Alireaza Tavassoli, Abbas Abdollahi, Elham Zarenezhad, Fatemeh Norouzi, Behnoosh Miladpour

Abstract read
In one paragraph

Article in International journal of biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Therapeutic Effect of Eugenol-Loaded Chitosan Nanoparticles AgainstInternational journal of biomaterials · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammad Javad TahmasebiStudent Research Committee, Fasa University of Medical Sciences, Fasa, Iran, fums.ac.ir.ORCID https://orcid.org/0000-0002-5883-5444
Mahmoud OsanlooDepartment of Medical Nanotechnology, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran, fums.ac.ir.ORCID https://orcid.org/0000-0002-1190-6874
Alireaza TavassoliDepartment of Pathology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran, fums.ac.ir.ORCID https://orcid.org/0000-0003-3466-8001
Abbas AbdollahiDepartment of Microbiology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran, fums.ac.ir.ORCID https://orcid.org/0000-0002-0832-6262
Elham ZarenezhadNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran, fums.ac.ir.ORCID https://orcid.org/0000-0003-2805-1910
Fatemeh NorouziDepartment of Microbiology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran, fums.ac.ir.ORCID https://orcid.org/0000-0002-7078-3616
Behnoosh MiladpourDepartment of Clinical Biochemistry, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran, fums.ac.ir.ORCID https://orcid.org/0000-0002-1978-1201

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Eugenol is a phenolic compound known for its antimicrobial, antifungal, and antioxidant properties. Its encapsulation in chitosan nanoparticles (EuChiNPs) enhances stability and therapeutic efficacy. Objectives: This study aimed to investigate the effects of EuChiNPs on Methods: EuChiNPs were synthesized and characterized using DLS, TEM, and FTIR techniques. A total of 42 male Wistar rats were divided into six groups, including controls, Results: The combination of EuChiNPs and standard antibiotics significantly reduced the expression of inflammatory markers interleukin-1 beta (IL-1β) and interleukin-8 (IL-8). Serum levels of IL-1β, IL-8, and TNF-α were markedly decreased in the combination group compared with antibiotics alone ( Conclusion: EuChiNPs demonstrated strong anti-inflammatory and antiapoptotic effects, especially when combined with standard antibiotics. This novel approach promises to improve

Indexed as

caspase-3chitosan nanoparticleseugenolH. pyloriIL-1βIL-8TNF-α

Identifiers

PMID41929357
PMCPMC13042343

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.