Evidence map›Paper›PMID 41929188›Full record

ArticlebioRxiv : the preprint server for biology2026

Cryo-EM structures of photosystem I with alternative quinones reveals new insight into cofactor selectivity.

Christian M Brininger, Jimin Wang, Vasily Kurashov, Brandon P Russell, Nikki Cecil M Magdaong, David F Iwig, Art van der Est, John H Golbeck, David J Vinyard, K V Lakshmi and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christian M BriningerDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0001-7278-4252
Jimin WangDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.ORCID 0000-0002-4504-8038
Vasily KurashovDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0003-1635-536X
Brandon P RussellDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803.ORCID 0000-0003-1382-9945
Nikki Cecil M MagdaongDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0003-3550-8288
David F IwigDepartment of Chemistry and Howard Hughes Medical Institute, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0001-8394-184X
Art van der EstDepartment of Chemistry, Brock University, St. Catharines, ON L2S 3A1.ORCID 0000-0002-6214-9260
John H GolbeckDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802.ORCID 0000-0002-3650-1582
David J VinyardDepartment of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803.ORCID 0000-0002-8058-5998
K V LakshmiDepartment of Chemistry and Chemical Biology and The Baruch '60 Center for Biochemical Solar Energy Research, Rensselaer Polytechnic Institute, Troy, NY 12180.ORCID 0000-0001-5443-9017
Christopher J GisrielDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0002-8011-0052

Funding

Photosystem II as a model protein for understanding metalloenzyme active site assemblyR00GM140174 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Christopher Gisriel · 2024 to 2026
$747k
NIGMS NIH HHS R00 GM140174
6 · The paper itself

Abstract

Quinones are an integral component of electron transfer processes in photosynthetic and mitochondrial respiratory proteins. One such photosynthetic protein, Photosystem I, is an essential photooxidoreductase found in all oxygenic phototrophs. To better understand quinone chemistry and to form a basis for protein engineering, the

Indexed as

cryo-EMelectron transferpartial occupancyPhotosystem IquinonesΔmenB variant

Identifiers

PMID41929188
PMCPMC13041885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.