Evidence map›Paper›PMID 41929186›Full record

ArticlebioRxiv : the preprint server for biology2026

Metabolic flexibility and an unusual route for peptidoglycan muramic acid recycling in mycobacteria.

Stefanos Stravoravdis, Bella R Carnahan, Rebecca A Gordon, Kimberly Wodzanowski, Karina Havaleshko, Elisabeth Fils-Aime, Rachel Putnik, Stephen Hyland, Catherine Leimkuhler Grimes, M Sloan Siegrist

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Stefanos StravoravdisDepartment of Microbiology, University of Massachusetts, Amherst; Amherst, MA, USA.
Bella R CarnahanDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Rebecca A GordonDepartment of Microbiology, University of Massachusetts, Amherst; Amherst, MA, USA.
Kimberly WodzanowskiDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Karina HavaleshkoDepartment of Microbiology, University of Massachusetts, Amherst; Amherst, MA, USA.
Elisabeth Fils-AimeDepartment of Microbiology, University of Massachusetts, Amherst; Amherst, MA, USA.
Rachel PutnikDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Stephen HylandDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Catherine Leimkuhler GrimesDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
M Sloan SiegristDepartment of Microbiology, University of Massachusetts, Amherst; Amherst, MA, USA.ORCID 0000-0002-8232-3246

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8M
Chemistry-Biology Interface Predoctoral Training Grant 2024-2029T32GM133395 · NIGMS · UNIVERSITY OF DELAWARE · PI Catherine Leimkuhler Grimes · 2019 to 2026
$3.7M
Chemistry-Biology Interface Predoctoral Training GrantT32GM139789 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ERIC Robert STRIETER · 2021 to 2026
$3.4M
Peptidoglycan Fragment Library to Investigate Innate Immune ResponsesR01AI191445 · NIAID · UNIVERSITY OF DELAWARE · PI Catherine Leimkuhler Grimes, HANS-CHRISTIAN REINECKER · 2025 to 2026
$1.6M
Metabolic carbohydrate cell wall probes for bacterial structure and immune recognition studiesU01CA221230 · NCI · UNIVERSITY OF DELAWARE · PI GRIMES, CATHERINE LEIMKUHLER · 2017 to 2019
$1.1M
Host proteins that interact with the BCG cell envelopeR21AI163949 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI GRIMES, CATHERINE LEIMKUHLER, SIEGRIST, MARY SLOAN · 2021 to 2022
$432k
Cell wall carbohydrate recycling in Mycobacterium tuberculosisR21AI188455 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Mary Sloan Siegrist · 2025 to 2026
$413k
NCI NIH HHS U01 CA221230NIAID NIH HHS R01 AI191445NIAID NIH HHS R21 AI163949NIAID NIH HHS R21 AI188455NIGMS NIH HHS P20 GM104316NIGMS NIH HHS T32 GM133395NIGMS NIH HHS T32 GM139789
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41929186
PMCPMC13041923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.