Evidence map›Paper›PMID 41929154›Full record

ArticlebioRxiv : the preprint server for biology2026

Using Cryogenic Electron Tomography (cryoET) to Determine Rubisco Polymerization Constants in α-Carboxysomes.

Wenxiang Cao, Kristy Rochon, Ryan H Gray, Luke Oltrogge, David F Savage, Enrique M De La Cruz, Lauren Ann Metskas

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenxiang CaoDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, United States.ORCID 0009-0001-3638-9586
Kristy RochonDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.ORCID 0000-0001-5692-6046
Ryan H GrayJames Tarpo Jr. and Margaret Tarpo Department of Chemistry, Purdue University, West Lafayette, IN, United States.
Luke OltroggeDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, United States.ORCID 0000-0001-5716-9980
David F SavageDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, United States.ORCID 0000-0003-0042-2257
Enrique M De La CruzDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, United States.ORCID 0000-0003-4798-2892
Lauren Ann MetskasDepartment of Biological Sciences, Purdue University, West Lafayette, IN, United States.ORCID 0000-0002-8073-6960

Funding

Pacific Northwest Center for Cryo-EM: Equipment SupplementR24GM154185 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI James E Evans, CLAUDIA SUSANA LOPEZ · 2024 to 2026
$21.5M
Actin filament mechanics and branched network turnoverR35GM136656 · NIGMS · YALE UNIVERSITY · PI ENRIQUE M DE LA CRUZ · 2020 to 2026
$4.0M
Purdue University Molecular Biophysics Training ProgramT32GM132024 · NIGMS · PURDUE UNIVERSITY · PI Angeline Marie Lyon, John Tesmer · 2019 to 2026
$2.0M
Determining the Role of csoS2 in Carboxysome Assembly and RegulationF32GM161096 · NIGMS · PURDUE UNIVERSITY · PI ROCHON, KRISTY · 2025 to 2025
$75k
NIGMS NIH HHS F32 GM161096NIGMS NIH HHS R24 GM154185NIGMS NIH HHS R35 GM136656NIGMS NIH HHS T32 GM132024
6 · The paper itself

Abstract

Bacteria microcompartments (BMCs) are pseudo-organelles comprised of a self-assembling, semipermeable protein shell, most commonly enclosing components of enzymatic pathways. α-Carboxysomes (α-CBs) are anabolic BMCs known for their role in sequestering Rubisco, the enzyme responsible for carbon fixation in plants, algae and bacteria, along with an upstream enzyme and an assembly protein. Rubisco has low selectivity for its substrate, CO

Indexed as

bacterial microcompartmentsBiological SciencesBiophysics and Computational Biologycarboxysomescryogenic electron tomographypolymerizationRubisco

Identifiers

PMID41929154
PMCPMC13041788

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.