Evidence map›Paper›PMID 41929081›Full record

ArticlebioRxiv : the preprint server for biology2026

Cross-disease genetic and epigenetic architecture of the

Katherine Fodder, Megha Murthy, Rohan de Silva, Towfique Raj, Kurt Farrell, Jack Humphrey, Conceição Bettencourt

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katherine FodderDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.ORCID 0009-0009-5289-0010
Megha MurthyDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.
Rohan de SilvaDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK.
Towfique RajDepartment of Genetics and Genomic Sciences, Icahn Genomics Institute, Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-9355-5704
Kurt FarrellNash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jack HumphreyDepartment of Genetics and Genomic Sciences, Icahn Genomics Institute, Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Conceição BettencourtDepartment of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.ORCID 0000-0001-9090-7690

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
Research Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI John Fonda Crary · 2020 to 2026
$31.0M
Human Biomarkers CoreU54NS123743 · NINDS · STANFORD UNIVERSITY · PI GITLER, AARON D., PETRUCELLI, LEONARD · 2021 to 2025
$8.2M
Learning the Regulatory Code of Alzheimer's Disease GenomesU01AG068880 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KNOWLES, DAVID ARTHUR, RAJ, TOWFIQUE · 2020 to 2024
$5.8M
The role of peripheral myeloid cells in Alzheimers diseaseR01AG054005 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RAJ, TOWFIQUE · 2017 to 2021
$4.1M
The Role of Myeloid Cells in Parkinson's DiseaseR01NS116006 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Towfique Raj · 2021 to 2026
$4.0M
Modeling the impact of regulatory and splicing variants on cellular function in Alzheimer's diseaseRF1AG065926 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRENNAND, KRISTEN JENNIFER, RAJ, TOWFIQUE · 2021 to 2021
$2.4M
COVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0M
Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
Modeling the impact of regulatory and splicing variants on cellular function in Alzheimer's diseaseR01AG065926 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRENNAND, KRISTEN JENNIFER, RAJ, TOWFIQUE · 2024 to 2025
$1.6M
A Comprehensive Genetic, Transcriptomic, and Immunohistochemical Analysis of PSPR01NS146414 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Kurt William Farrell · 2026 to 2026
$670k
The impact of Alzheimer's disease susceptibility alleles on microglia transcriptomeR21AG063130 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DE WITTE, LOTJE DOROTHEE, RAJ, TOWFIQUE · 2020 to 2020
$599k
NCATS NIH HHS UL1 TR004419NIA NIH HHS K01 AG070326NIA NIH HHS P30 AG066514NIA NIH HHS R01 AG054005NIA NIH HHS R01 AG065926NIA NIH HHS R21 AG063130NIA NIH HHS R21 AG091272NIA NIH HHS R56 AG088669NIA NIH HHS RF1 AG065926NIA NIH HHS U01 AG068880NIH HHS S10 OD026880NIH HHS S10 OD030463NINDS NIH HHS R01 NS116006NINDS NIH HHS R01 NS146414NINDS NIH HHS U54 NS123743
6 · The paper itself

Abstract

Myelin oligodendrocyte basic protein (

Identifiers

PMID41929081
PMCPMC13041890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.