Evidence map›Paper›PMID 41929038›Full record

ArticlebioRxiv : the preprint server for biology2026

PPARγ-dependent and -independent regulation of methionine metabolism by diet-induced obesity and fasting in male mice.

Izabela Hawro, Samuel M Lee, Rhonda D Kineman, Jose Cordoba-Chacon

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Izabela HawroDepartment of Medicine. Division of Endocrinology, Diabetes and Metabolism. University of Illinois at Chicago, Chicago. IL.
Samuel M LeeDepartment of Medicine. Division of Endocrinology, Diabetes and Metabolism. University of Illinois at Chicago, Chicago. IL.
Rhonda D KinemanResearch and Development, Jesse Brown VA Medical Center, Chicago, IL.
Jose Cordoba-ChaconDepartment of Medicine. Division of Endocrinology, Diabetes and Metabolism. University of Illinois at Chicago, Chicago. IL.ORCID 0000-0001-8787-2706

Funding

PPARgamma-regulated mechanisms in hepatocytes that promote NAFLDR01DK131038 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jose Cordoba-Chacon · 2022 to 2026
$2.1M
NIDDK NIH HHS R01 DK131038
6 · The paper itself

Abstract

Metabolic dysfunction-associated steatohepatitis (MASH) is associated with increased expression of peroxisome proliferator-activated receptor gamma (PPARγ,

Indexed as

diet-induced obesityfastingmethionine metabolismthiazolidinediones

Identifiers

PMID41929038
PMCPMC13042000

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.