Evidence map›Paper›PMID 41929005›Full record

ArticlebioRxiv : the preprint server for biology2026

Molecularly defined subpopulations of leptin receptor neurons dissociate the control of food intake from blood pressure.

Allison M Duensing, Dylan Belmont-Rausch, Abigail J Tomlinson, Aiden Crowley, Frederike Sass, Elizabeth Heaton, Bernd Coester, Jenny M Brown, Shad Hassan, Zhe Wu and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Allison M DuensingDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI.
Dylan Belmont-RauschNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK.
Abigail J TomlinsonDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI.
Aiden CrowleyDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI.
Frederike SassDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI.
Elizabeth HeatonDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI.
Bernd CoesterNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK.
Jenny M BrownNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK.
Shad HassanNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK.
Zhe WuDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI.
Nathan QiDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI.
David P OlsonDepartment of Pediatrics, University of Michigan, Ann Arbor, MI.
Paul V SabatiniDepartment of Medicine, McGill University, Montreal, Quebec.
Martin G MyersDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI.
Tune H PersNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen DK.

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
MOLECULAR DETERMINANTS OF LEPTIN RECEPTOR/JAK2 SIGNALINGR01DK056731 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MYERS, MARTIN G · 1999 to 2025
$6.0M
Thermoregulatory circuits that regulate feedingR01DK124238 · NIDDK · UNIVERSITY OF WASHINGTON · PI GREGORY J MORTON, Tune Hannes Pers · 2020 to 2026
$3.9M
Metabolic Phenotyping in Live Models of Obesity and DiabetesU2CDK135066 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Nathan R. Qi · 2023 to 2026
$3.5M
Mechanisms of action for dorsomedial hypothalamic Lepr-Glp1r neurons that control feeding and energy balanceF31DK137390 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DUENSING, ALLISON · 2023 to 2025
$145k
NIDDK NIH HHS F31 DK137390NIDDK NIH HHS P30 DK020572NIDDK NIH HHS R01 DK056731NIDDK NIH HHS R01 DK124238NIDDK NIH HHS U2C DK135066
6 · The paper itself

Abstract

While previous studies have suggested that leptin regulates cardiovascular function independently of body weight, the specific leptin receptor (

Identifiers

PMID41929005
PMCPMC13041920

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.