ArticlebioRxiv : the preprint server for biology2026
Cross-coronavirus host susceptibility loci influence disease severity through immune mediators.
Ellen L Risemberg, Sarah R Leist, Alexandra Schäfer, Kalika D Kamat, Timothy A Bell, Pablo Hock, Kara L Jensen, Colton L Linnertz, Darla R Miller, Ginger D Shaw and 4 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Sarah R LeistDepartment of Epidemiology, UNC Chapel Hill.
Alexandra SchäferDepartment of Epidemiology, UNC Chapel Hill.
Kalika D KamatDepartment of Genetics, UNC Chapel Hill.
Timothy A BellDepartment of Genetics, UNC Chapel Hill.
Pablo HockDepartment of Genetics, UNC Chapel Hill.
Kara L JensenDepartment of Epidemiology, UNC Chapel Hill.
Colton L LinnertzDepartment of Genetics, UNC Chapel Hill.
Darla R MillerDepartment of Genetics, UNC Chapel Hill.
Ginger D ShawDepartment of Genetics, UNC Chapel Hill.
Fernando Pardo Manuel de VillenaDepartment of Genetics, UNC Chapel Hill.
Ralph S BaricDepartment of Epidemiology, UNC Chapel Hill.
Martin T FerrisDepartment of Genetics, UNC Chapel Hill.
Funding
Unlocking Zika Virus Immune Control and Pathogenesis with the Collaborative CrossU19AI100625 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HEISE, MARK T · 2012 to 2021
$36.6MSystems Genetics of TuberculosisP01AI181898 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CHRISTOPHER M SASSETTI · 2024 to 2026
$10.5MGenetic Analysis of COVID-19 Susceptibility and Resistance Determinants in the Collaborative CrossR01AI157253 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BARIC, RALPH S, HEISE, MARK T · 2020 to 2024
$3.8MStatistical Modeling of Multiparental and Genetic Reference PopulationsR35GM127000 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Valdar · 2018 to 2026
$3.1MPredoctoral Training Program in Bioinformatics and Computational BiologyT32GM135123 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Michael Isaiah Love, William Valdar · 2021 to 2026
$1.7MNIAID NIH HHS P01 AI181898NIAID NIH HHS R01 AI157253NIAID NIH HHS U19 AI100625NIGMS NIH HHS R35 GM127000NIGMS NIH HHS T32 GM135123
6 · The paper itselfAbstract
Severe disease following infection with SARS-CoV or SARS-CoV-2 is driven in part by genetically regulated immune responses that promote lung injury. Previously, we showed that genetic risk for severe disease is conserved across viruses and between mouse and human, identifying the
Identifiers
PMID41928982
PMCPMC13041847
What OpenQuestion holds
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