Evidence map›Paper›PMID 41928924›Full record

ArticlebioRxiv : the preprint server for biology2026

MscM uses a novel gating mechanism for bacterial mechanosensitive channels.

Giorgos Hiotis, Thomas Walz

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giorgos HiotisLaboratory of Molecular Electron Microscopy, The Rockefeller University; New York, NY, USA.ORCID 0000-0002-8731-7427
Thomas WalzLaboratory of Molecular Electron Microscopy, The Rockefeller University; New York, NY, USA.ORCID 0000-0003-2606-2835

Funding

Elucidating the gating mechanisms of bacterial mechanosensitive channelsR01GM144581 · NIGMS · ROCKEFELLER UNIVERSITY · PI THOMAS WALZ · 2023 to 2026
$2.0M
NIGMS NIH HHS R01 GM144581
6 · The paper itself

Abstract

The mechanosensitive channel of small conductance (MscS) is the founding member of the family of MscS-like channels, which share a structurally conserved core but feature additional structural elements that define their specific channel characteristics. Here, we characterize the structure and function of the

Identifiers

PMID41928924
PMCPMC13041993

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.