Evidence map›Paper›PMID 41928854›Full record

ArticleFrontiers in reproductive health2026

Investigating discrepancies in accuracy, agreement and interpretability for single-frame embryo classification tasks conducted by embryologists and deep learning models.

Radhika Kakulavarapu, Erwan Delbarre, Akriti Sharma, David Jahanlu, Michael A Riegler, Trine B Haugen, Mario Iliceto, Mette H Stensen

Abstract read
In one paragraph

Article in Frontiers in reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Radhika KakulavarapuDepartment of Life Sciences and Health, Faculty of Health Sciences, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Erwan DelbarreDepartment of Life Sciences and Health, Faculty of Health Sciences, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Akriti SharmaSimula Research Laboratory, Oslo, Norway.
David JahanluDepartment of Life Sciences and Health, Faculty of Health Sciences, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Michael A RieglerSimula Research Laboratory, Oslo, Norway.
Trine B HaugenDepartment of Life Sciences and Health, Faculty of Health Sciences, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Mario IlicetoVolvat Spiren, Oslo, Norway.
Mette H StensenVolvat Spiren, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Artificial intelligence tools show promise in supporting clinical decision making, but their safe use requires evaluation of not only accuracy, but also agreement with experts and interpretability of model decisions. The aim of this study was to evaluate the accuracy and agreement of human embryologists and deep learning models in embryo stage classification, and to explore interpretability through explainable artificial intelligence. Methods: A retrospective, single-center study used single-frame embryo images ( Results: Embryologists achieved higher accuracy (89.9%) than ResNet-34 (78.8%, Conclusions: These findings highlight the need for evaluation frameworks that integrate accuracy, agreement and interpretability to support safe and transparent development of artificial intelligence tools in assisted reproduction technology.

Indexed as

accuracyagreementdeep learningembryo assessmentinterpretability

Identifiers

PMID41928854
PMCPMC13040276

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.