Evidence map›Paper›PMID 41928453›Full record

ArticleOncoimmunology2026

Sialic acid

Jesper van Eck van der Sluijs, Anne H C Valk, Eline J H van Houtum, Esther D Kers-Rebel, Maaike Looman, Willemijn Hobo, Anna E Marneth, Harry Dolstra, Lune van den Boogaard, Christian Büll and 2 more

Abstract read
In one paragraph

Article in Oncoimmunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jesper van Eck van der SluijsDepartment of Radiation Oncology, Laboratory of Radiotherapy & OncoImmunology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0003-3136-7799
Anne H C ValkDepartment of Radiation Oncology, Laboratory of Radiotherapy & OncoImmunology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0002-6190-0438
Eline J H van HoutumDepartment of Radiation Oncology, Laboratory of Radiotherapy & OncoImmunology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0001-9037-4388
Esther D Kers-RebelDepartment of Radiation Oncology, Laboratory of Radiotherapy & OncoImmunology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.
Maaike LoomanDepartment of Radiation Oncology, Laboratory of Radiotherapy & OncoImmunology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.
Willemijn HoboDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.
Anna E MarnethDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0001-9065-0581
Harry DolstraDepartment of Laboratory Medicine, Laboratory of Hematology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0002-3998-687X
Lune van den BoogaardDepartment of Radiation Oncology, Laboratory of Radiotherapy & OncoImmunology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.ORCID 0009-0004-9060-2925
Christian BüllDepartment of Biomolecular Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands.ORCID 0000-0001-7785-2920
Lenneke A M CornelissenDepartment of Radiation Oncology, Laboratory of Radiotherapy & OncoImmunology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0003-2210-1606
Gosse J AdemaDepartment of Radiation Oncology, Laboratory of Radiotherapy & OncoImmunology, Radboud Institute for Medical Innovation, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0002-6750-1665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The glyco-immune checkpoints Siglec-7 and Siglec-9 have received considerable interest as targets for cancer immunotherapy. How Siglec-7/9-sialic acid

Indexed as

Antigens, CDAntigens, Differentiation, B-LymphocyteAntigens, Differentiation, MyelomonocyticKiller Cells, NaturalLectinsMelanomaN-Acetylneuraminic AcidSialic Acid Binding Immunoglobulin-like LectinsCell Line, TumorHumansJurkat CellsLeukemia, Myeloid, AcuteLigandsSignal TransductionTetraspanin 29Antigens, CDAntigens, Differentiation, B-LymphocyteAntigens, Differentiation, MyelomonocyticCD9 protein, humanLectinsLigandsN-Acetylneuraminic AcidSialic Acid Binding Immunoglobulin-like LectinsSIGLEC7 protein, humanSIGLEC9 protein, humanTetraspanin 29acute myeloid leukemiaanti-tumor immunitycis-ligand, sialic acidimmune checkpointimmunotherapymelanomanatural killer cellsSiglec-7Siglec-9

Identifiers

PMID41928453
PMCPMC13051614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.