ArticleBMC musculoskeletal disorders2026
Gait and posturographic parameters of children with achondroplasia - a long-term pilot study.
Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Walking and maintaining balance are essential for participating in daily life. For children with achondroplasia, reaching these milestones is with a delay and during growth, challenges persist for those skills. However, the impact of developmental changes on gait and balance in this population has not yet been investigated longitudinally. Therefore, this study aimed to examine the influence of growth on gait pattern and postural control in children with achondroplasia over a two-year period. 6 children with achondroplasia (whereas 5 are treated with vosoritide, a growth promoting peptide) and 24 children of average height participated in a 3D gait analysis and static bipedal posturographic (eyes open/closed and foam pad with eyes open/closed) measurements every six months. Using Nonparametric Analysis of Longitudinal Data and the smallest real differences, changes over time and between the cohorts were investigated. Results showed that the growth development between the cohorts were similar. Still, the key characteristics of achondroplasia were prominent and revealed significant differences for the anthropometric parameters. Spatio- temporal, kinematic parameters revealed additional significant differences for known characteristics like gait velocity, step- and stride length, cadence, step & stride time, stance- and swing phase and single support time, between the cohorts. Finally, posturographic parameters present significant differences in the foam pad eyes closed condition between the cohorts. Overall, all children show considerable variability for gait and posturographic parameters, with greater variability present children with achondroplasia. The findings of this work indicate that there are no general differences in the growth curves between children with achondroplasia and children of average height. However, the different baseline of both cohorts, with the vosoritide treatment and the already changed gait pattern of achondroplasia must be considered as additional factors. Further research is needed to investigate broader age groups, possible gender differences and greater sample sizes, e.g. through a multi-center study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.