Evidence map›Paper›PMID 41928169›Full record

Observational studyBMC ophthalmology2026

Comparison of refractive parameters provided by a new open field aberrometer and the subjective refraction.

Antonio Martinez-Abad, Pilar Yebana-Rubio, Ana Belén Plaza-Puche, Alejandra Eliana Rodríguez, Marina José-Martínez, David P Piñero, Jorge L Alió, Mario Cantó-Cerdán

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Antonio Martinez-AbadResearch and Development Department, Vissum Grupo Miranza, Calle Cabañal 1, Alicante, 03016, Spain. antonio.martinez@vissum.com.ORCID http://orcid.org/0000-0002-5684-1090
Pilar Yebana-RubioResearch and Development Department, Vissum Grupo Miranza, Calle Cabañal 1, Alicante, 03016, Spain.
Ana Belén Plaza-PucheDepartment of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, 03690, Spain.
Alejandra Eliana RodríguezResearch and Development Department, Vissum Grupo Miranza, Calle Cabañal 1, Alicante, 03016, Spain.
Marina José-MartínezResearch and Development Department, Vissum Grupo Miranza, Calle Cabañal 1, Alicante, 03016, Spain.
David P PiñeroDepartment of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, 03690, Spain.
Jorge L AlióResearch and Development Department, Vissum Grupo Miranza, Calle Cabañal 1, Alicante, 03016, Spain.
Mario Cantó-CerdánResearch and Development Department, Vissum Grupo Miranza, Calle Cabañal 1, Alicante, 03016, Spain.

Funding

European Union's Horizon 2020 research and innovation programme 878748
6 · The paper itself

Abstract

purposeTo compare and evaluate the agreement between refractive measurements obtained by the new open-field OFA-Osiris (CSO®) aberrometer and the subjective refraction.

methodsObservational, prospective, cross-sectional study involving healthy eyes. Subjects underwent a subjective refraction and ocular aberrometry using the OFA-Osiris device. Sphere, cylinder, and axis values obtained from both methods were converted to polar notation using M, J0 and J45 vectors. Refractive data from ocular aberrometry were extracted at 4 and 5 mm pupil diameters. The Wilcoxon sum-rank test was used to compare the methods, and Bland-Altman plots were used for the agreement analysis.

results183 eyes from 183 subjects (mean age: 24.9 ± 5.2 years) were included. No significant differences were found between the subjective and the objective refractive obtained with the OFA-Osiris aberrometer considering a pupil diameter of 5 mm for astigmatic parameters (J0 0.01 ± 0.19 D vs. 0.02 ± 0.26 D, J45 0.03 ± 0.21 D vs. 0.01 ± 0.24, p > 0.05) but a significant difference were observed in terms of spherical equivalent (M -1.42 ± 2.06 D vs. -1.50 ± 2.17 D, p: 0.001) When considering a pupil diameter of 4 mm for the objective refraction measurement, no significant differences were observed in any refractive parameter (M -1.42 ± 2.06 D vs. 1.42 ± 2.25, J0 0.01 ± 0.19 D vs. 0.01 ± 0.265 D, J45 0.03 ± 0.21 D vs. 0.01 ± 0.26, p > 0.05). Bland-Altman plots revealed 95% confidence intervals higher than 0.50 D.

conclusionAberrometric refraction provided by the new open-field aberrometer, OFA-Osiris, showed general good agreement with subjective refraction – particularly for a pupil diameter of 4 mm – but not being totally interchangeable by the presence of some unacceptable cases and recommending the subjective refraction as gold standard for refractive evaluation.

Indexed as

AberrometryRefraction, OcularRefractive ErrorsAdultCross-Sectional StudiesFemaleHumansMaleProspective StudiesReproducibility of ResultsYoung AdultAberrometerAberrometryObjective refractionOcular refractionPupil diameterSubjective refractionValidation

Identifiers

PMID41928169
PMCPMC13169636

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.