Evidence map›Paper›PMID 41928132›Full record

ArticleBMC nephrology2026

Comparison of estimated and measured GFR in pediatric CKD patients transitioning from adolescence to adulthood: results from KNOW-PedCKD.

Seon Hee Lim, Eujin Park, Kyung Hee Han, Ji Yeon Song, Seong Heon Kim, Naye Choi, Heeyeon Cho, Jeong Yeon Kim, Jae Il Shin, Keum Hwa Lee and 10 more

Abstract readComparative Study
In one paragraph

Article in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

20 authors.

Seon Hee LimDepartment of Pediatrics, Pusan National University Children's Hospital, Yangsan, Republic of Korea.
Eujin ParkDepartment of Pediatrics, Korea University Guro Hospital, Seoul, Republic of Korea.
Kyung Hee HanDepartment of Pediatrics, Jeju University Hospital, Jeju, Republic of Korea.
Ji Yeon SongDepartment of Pediatrics, Pusan National University Children's Hospital, Yangsan, Republic of Korea.
Seong Heon KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Naye ChoiDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Heeyeon ChoDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Jeong Yeon KimDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Jae Il ShinDivision of Pediatric Nephrology, Severance Children's Hospital, Seoul, Republic of Korea.
Keum Hwa LeeDivision of Pediatric Nephrology, Severance Children's Hospital, Seoul, Republic of Korea.
Min Hyun ChoDepartment of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Min Ji ParkDepartment of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Hee Sun BaekDepartment of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Joo Hoon LeeDepartment of Pediatrics, Asan Medical Center Children's Hospital, Ulsan University, College of Medicine, Seoul, Republic of Korea.
Jiwon JungDepartment of Pediatrics, Asan Medical Center Children's Hospital, Ulsan University, College of Medicine, Seoul, Republic of Korea.
Eun Mi YangDepartment of Pediatrics, Chonnam National University Hospital and Medical School, Gwangju, South Korea.
Ji Hyun KimDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam, South Korea.
Il-Soo HaDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Hee Gyung KangDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea.
Yo Han AhnDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea. yhahn@snu.ac.kr.

Funding

National Institute of Health (NIH) 2025-E110100
6 · The paper itself

Abstract

backgroundAccurate estimation of glomerular filtration rate (eGFR) is essential for managing pediatric chronic kidney disease (CKD). While multiple eGFR equations are used clinically, their reliability in adolescents transitioning to adulthood with pediatric-onset CKD remains uncertain. This study aimed to evaluate the accuracy of 10 eGFR equations against measured GFR (mGFR) values in South Korean adolescents and young adults with CKD using data from the KoreaN Cohort Study for Outcomes in Patients With Pediatric Chronic Kidney Disease (KNOW-PedCKD) cohort.

methodsPatients aged ≥ 15 years who underwent mGFR testing were included in the KNOW-PedCKD study. mGFR was determined using plasma clearance of

resultsThe analysis encompassed 187 mGFR measurements from 82 patients (median age 18.4 years, interquartile range (IQR) 16.5-20.8; 75.9% male). Median mGFR was 42.3 (19.3-70.5) mL/min/1.73 m

conclusionsThe eGFR equations covering children - particularly U25

Indexed as

Glomerular Filtration RateRenal Insufficiency, ChronicAdolescentAdultChromium RadioisotopesCohort StudiesFemaleHumansMaleReproducibility of ResultsRepublic of KoreaTechnetium Tc 99m PentetateYoung AdultChromium RadioisotopesTechnetium Tc 99m PentetateAdolescenceChronic kidney diseaseGlomerular filtration rate

Identifiers

PMID41928132
PMCPMC13169761

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