ArticleBDJ open2026
Dental, mandibular and parotid gland radiation doses in curatively treated head and neck squamous cell carcinoma: a retrospective cohort study.
Article in BDJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
background and purposeRadiation therapy (RT) is a cornerstone of head and neck squamous cell carcinoma (HNSCC) treatment, often used alongside surgical approaches, delivering curative doses between 50-70 Gy. Pre-RT dental screenings aim to prevent oral complications by extracting teeth with poor prognosis, particularly in high-dose areas exceeding 40 Gy. The aim of the present study was to measure the planned radiation doses received on dentition during definitive or postoperative radiation therapy for HNSCC. MATERIAL AND
methodsThis retrospective study analyzed 91 HNSCC cases treated with RT at Oulu University Hospital (2018-2021), assessing radiation doses to dentition, mandible, and parotid glands across different tumor sites.
resultsResults showed that ipsilateral RT spared contralateral and frontal dental regions more effectively than bilateral RT, particularly in oral cavity and oropharyngeal cancers. Conversely, hypopharyngeal and laryngeal cancers rarely exposed dentition to doses above 40 Gy. Bilateral RT often exceeded the 40 Gy threshold in mandibular and parotid regions, particularly in oral cavity cancers, underscoring the need for precise dose planning to balance tumor control with oral health preservation.
conclusionThe findings highlight that ipsilateral RT can reduce the need for pre-RT dental extractions in contralateral regions and provide a basis for optimizing dental care strategies. By understanding dose distributions, balance can be addressed between minimizing oral health impacts and ensuring effective HNSCC treatment.
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