Evidence map›Paper›PMID 41927341›Full record

ArticleAJNR. American journal of neuroradiology2026

Comparative Analysis of Middle Ear Prostheses Using Photon-Counting Detector CT versus Conventional CT.

Arka Dutta, Paul J Farnsworth, Shuai Leng, John C Benson, Matthew L Carlson, Blake A Kassmeyer, Ian T Mark, John I Lane

Abstract readComparative Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arka DuttaFrom the Department of Radiology (A.D., P.J.F., S.L., J.C.B., I.T.M., J.L.L.), Mayo Clinic, Rochester, Minnesota Arkadutta@gmail.com.ORCID 0000-0002-6523-1470
Paul J FarnsworthFrom the Department of Radiology (A.D., P.J.F., S.L., J.C.B., I.T.M., J.L.L.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-3955-6722
Shuai LengFrom the Department of Radiology (A.D., P.J.F., S.L., J.C.B., I.T.M., J.L.L.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-6453-9481
John C BensonFrom the Department of Radiology (A.D., P.J.F., S.L., J.C.B., I.T.M., J.L.L.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-4038-5422
Matthew L CarlsonDepartment of Otolaryngology-Head and Neck Surgery (M.L.C.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-4925-8593
Blake A KassmeyerDepartment of Quantitative Health Sciences (B.A.K.), Mayo Clinic, Rochester, Minnesota.
Ian T MarkFrom the Department of Radiology (A.D., P.J.F., S.L., J.C.B., I.T.M., J.L.L.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0002-4036-2992
John I LaneFrom the Department of Radiology (A.D., P.J.F., S.L., J.C.B., I.T.M., J.L.L.), Mayo Clinic, Rochester, Minnesota.ORCID 0000-0001-5874-633X

Funding

High-resolution in vivo imaging of inner ear using photon-counting-detector computed tomography and artificial intelligenceR01DC022228 · NIDCD · MAYO CLINIC ROCHESTER · PI Matthew L Carlson, Shuai Leng · 2025 to 2026
$1.5M
NIDCD NIH HHS R01 DC022228
6 · The paper itself

Abstract

background and purposeMiddle ear prostheses are among the smallest implanted medical devices, with diameters as small as 0.25 mm. Accurate postoperative imaging is critical for assessing prosthesis placement, detecting complications such as dislodgement or extrusion, and informing potential revisions. Conventional energy-integrating detector CT (EID-CT) is traditionally used for imaging these implants; however, with the recent clinical use of photon-counting detector CT (PCD-CT), further analysis on multiple parameters is required to assess future utility. This study compares the spatial resolution and visualization quality of middle ear prostheses between EID-CT and PCD-CT. We hypothesize that PCD-CT will provide superior spatial resolution of prostheses, allowing for more accurate postoperative assessments to facilitate improved clinical decision-making. MATERIALS AND

methodsThis retrospective study included 10 patients with various middle ear prostheses, including total ossicular replacement prostheses, partial ossicular replacement prostheses (PORP), stapes prostheses, and the middle ear portion of cochlear implants. Each patient underwent temporal bone imaging on both EID-CT and PCD-CT scanners using institutional high-resolution protocols. A total of 30 line profiles were analyzed, with peak intensity (HU) and full width at half maximum (FWHM) calculated from the intensity curves along the prosthetic shafts. Paired

resultsPCD-CT demonstrated significantly higher mean peak intensity values (4855.8 [SD, 3944.3] HU ) compared with EID-CT (2498.7 [SD, 2135.9] HU), with a mean difference of 2357 HU (95% CI, 77-4638; HU;

conclusionsPCD-CT demonstrates advantages in spatial resolution and image quality over conventional EID-CT for postoperative evaluation of middle ear prostheses. Enhanced visualization may improve diagnostic confidence and enable more accurate postoperative assessment and complication detection.

Indexed as

Ossicular ProsthesisTomography, X-Ray ComputedAdultAgedFemaleHumansMaleMiddle AgedPhotonsReproducibility of ResultsRetrospective StudiesSensitivity and Specificity

Identifiers

PMID41927341
PMCPMC13045908

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