ArticleJournal of AOAC International2026
Simultaneous Analysis of Major Anthocyanins in Aronia-Containing Food Supplements by HPLC: A Greenness and Whiteness Approach.
Article in Journal of AOAC International, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAronia melanocarpa fruit is a valuable component of a healthy diet due to its rich antioxidant activity and high content of bioactive compounds. Recently, many food products and food supplements have emerged due to the increasing interest in aronia.
objectiveIn this study, a liquid chromatography method for the simultaneous quantification of the anthocyanins cyanidin-3-galactoside, cyanidin-3-arabinoside, and cyanidin-3-glucoside in aronia was developed.
methodsIn this high-performance liquid chromatography (HPLC) system, the simultaneous analysis of the three active substances was performed on a Phenomenex, Gemini C18 (150 × 4.6 mm, 5 µm) column at 30°C. As a mobile phase, 1% glacial acetic acid-ACN-phosphoric acid (510:485:5, h/h/h) and 0.5% phosphoric acid solutions were used, and a gradient system was applied at a flow rate of 0.8 mL/min.
resultsThe developed method was validated according to ICH Q2 (R1) guidelines. Cyanidin-3-galactoside and cyanidin-3-arabinoside were found linearly in the concentration ranges of 2.5-12.5 µg/mL, and cyanidin-3-glucoside was found in the range of 0.25-4 µg/mL (r > 0.99).
conclusionsThe developed and validated method was successfully applied to the analysis of samples containing aronia. Moreover, the proposed chromatographic method was assessed in terms of greenness and whiteness using the Analytical Greenness software and the White Analytical Chemistry (WAC) model. HIGHLIGHTS: A reliable HPLC method was developed for simultaneous quantification of three major anthocyanins in Aronia melanocarpa. The validated method was successfully applied to real aronia-containing samples.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.