Evidence map›Paper›PMID 41926365›Full record

ArticlePloS one2026

Comparison of stationary digital chest tomosynthesis to portable chest radiographs: A patient study.

Courtney Wing, Elias Taylor Gunnell, Alex Billingsley, Umer Ahmed, Christina Inscoe, Muthu Sakthivel, Bryan Hoag, Ertan Pamuklar, Thad Benefield, Jianping Lu and 3 more

Abstract readComparative Study
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Courtney WingDepartment of Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID https://orcid.org/0009-0009-5436-9907
Elias Taylor GunnellDepartment of Radiology, The Medical University of South Carolina, Charleston, South Carolina, United States of America.ORCID https://orcid.org/0000-0001-6979-0555
Alex BillingsleyJoint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Umer AhmedDepartment of Radiology, Boston Medical Center, Boston, Massachusetts, United States of America.
Christina InscoeDepartment of Physics and Astronomy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Muthu SakthivelDepartment of Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.ORCID https://orcid.org/0000-0002-6257-884X
Bryan HoagDepartment of Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Ertan PamuklarDepartment of Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Thad BenefieldDepartment of Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Jianping LuDepartment of Physics and Astronomy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Xiaohui WangCarestream Health Inc., Rochester, New York, United States of America.
Otto ZhouDepartment of Physics and Astronomy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Yueh Z LeeDepartment of Radiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPortable chest radiographs are a vital tool for clinical evaluation. However, their value remains limited due to overlapping anatomical structures obscuring underlying pathologies. Chest tomosynthesis has been proposed as an alternative to CT for high resolution chest imaging; however, a portable tomosynthesis unit is currently lacking in the standard of care. Utilizing a carbon nanotube linear x-ray source array, our team has developed a stationary digital chest tomosynthesis (s-DCT) unit that enables tomosynthesis imaging without need for a moving x-ray source during image acquisition. PURPOSE: The goal of our study was to evaluate the performance of portable s-DCT in patients with concurrent portable radiographs and recent cross-sectional chest CT imaging.

methodsThis study recruited twenty-seven outpatients with recent chest CT images. Twenty-two patients were imaged with a conventional radiograph unit and the s-DCT system. Three board-certified thoracic radiologists rated their confidence in evaluating ten criteria: nine anatomic criteria and one on indwelling hardware. Readers were asked if information was gained from chest tomosynthesis, and if a follow-up CT was recommended. Random effects modeling was performed to assess factors contributing to reader confidence.

resultsTwenty-two adult patients were successfully imaged. Overall, reader confidence with s-DCT was significantly higher than CXR (p = < 0.001). Higher confidence in tomosynthesis was associated with perception that tomosynthesis gave additional information over CXR (p = 0.05). There was no significant trend toward not recommending a CT (p = 0.47).

conclusionStationary digital chest tomosynthesis is a superior alternative to portable chest x-ray for patients that cannot undergo CT examination.

Indexed as

Portable X-RayRadiographic Image EnhancementRadiography, ThoracicTomography, X-Ray ComputedAdultAgedAged, 80 and overFemaleHumansMaleMiddle Aged

Identifiers

PMID41926365
PMCPMC13046129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.