Evidence map›Paper›PMID 41926067›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2026

Power Profiles of an Extended Depth of Focus Contact Lens for Myopia Management.

Veronica Noya-Padin, Annabelle J Mawhinney, Phillip J Buckhurst, Hugo Pena-Verdeal, Craig McNeile, Stephen D Hall, Hetal D Buckhurst

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Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Veronica Noya-PadinFacultade de Óptica e Optometría, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Annabelle J MawhinneyFaculty of Health, University of Plymouth, Plymouth, UK.
Phillip J BuckhurstFaculty of Health, University of Plymouth, Plymouth, UK.
Hugo Pena-VerdealFacultade de Óptica e Optometría, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Craig McNeileCentre for Mathematical Sciences, University of Plymouth, Plymouth, UK.
Stephen D HallFaculty of Health, University of Plymouth, Plymouth, UK.
Hetal D BuckhurstFaculty of Health, University of Plymouth, Plymouth, UK. hetal.buckhurst@plymouth.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo characterise the optical power profiles of an extended depth of focus (EDOF) contact lens (MYLO, Mark'ennovy) for myopia management across its full range of labelled powers and fitting parameters.

methodsPower profiles of 91 MYLO lenses were measured using the NIMOevo® instrument. Lenses ranged in labelled power from -1.00 to -10.00 D, total diameters (TD) from 13.50 to 15.50 mm and back optic zone radii (BOZR) from 7.1 to 9.8 mm. Central thickness (CT) was assessed using spectral-domain optical coherence tomography. Lens power profiles were fitted with piecewise cubic splines, and peaks and troughs were identified using both semi- and fully-automated inflection-point detection. Zernike polynomial fitting, applied at enhanced resolution, was used to derive power within the central 0.50 mm radius.

resultsAll lenses demonstrated a damped sine-wave power profile, featuring three consistent peaks and troughs superimposed on a general trend toward peripheral minus power. The location and relative magnitude of these features remained highly consistent across all combinations of lens power, TD and BOZR. Central zone analysis revealed a mean relative hyperopic defocus of 1.24 ± 0.79 D within the central 0.25 mm radius, followed by a myopic shift of 0.41 ± 0.38 D in the 0.25-0.50 mm annulus, resulting in a near-emmetropic outcome (0.08 ± 0.38 D) across the full central 0.00-0.50 mm region. CT was not correlated with labelled power.

conclusionsThe MYLO lens demonstrated a stable and predictable optical profile across a broad range of fitting parameters, indicating that changes in lens power or parameters do not impact its optical performance. The study highlights the need for refined standards in the evaluation of power profiles of EDOF contact lenses.

Indexed as

Contact LensesMyopiaRefraction, OcularEquipment DesignHumansTomography, Optical CoherenceContact lensesExtended depth of focusMyopiaMyopia managementPower profiles

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.