Evidence map›Paper›PMID 41925850›Full record

GuidelineHNO2026

[On the German S3 guideline on perioperative and periinterventional antibiotic prophylaxis].

Sarina K Müller, Benedikt Hofauer

Abstract readPractice GuidelineEnglish Abstract
In one paragraph

Guideline in HNO, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarina K MüllerHals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Universitätsklinik Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Waldstraße 1, 91054, Erlangen, Deutschland. Sarina.Mueller@uk-erlangen.de.
Benedikt HofauerHals-Nasen-Ohrenklinik, Kopf- und Halschirurgie, Medizinische Universität Innsbruck, Innsbruck, Österreich.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In December 2024, the German S3 guideline on perioperative and periinterventional antibiotic prophylaxis (PAP) was published after years of interdisciplinary collaboration. This guideline was developed with the involvement of a delegation from the German Society of Otorhinolaryngology, Head and Neck Surgery, because it is particularly important for our medical specialty: in interdisciplinary comparison, otorhinolaryngologists traditionally prescribe a relatively high number of antibiotics in perioperative settings. The S3 guideline is based on randomized controlled trials and review articles evaluated by the Robert Koch Institute using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology. The aim of this CME article is to present the S3 guideline with a focus on the indications for PAP, its duration, risk assessment, and selection of the appropriate antibiotic. Practical application examples and a dosage table further illustrate these points.

Indexed as

Anti-Bacterial AgentsAntibiotic ProphylaxisPerioperative CarePractice Guidelines as TopicSurgical Wound InfectionGermanyHumansAnti-Bacterial AgentsAntibiotic resistanceCephalosporinsPenicillinsPostoperative complicationsSurgical site infection

Identifiers

PMID41925850
PMCPMC13109251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.