Evidence map›Paper›PMID 41925796›Full record

SynthesisJournal of robotic surgery2026

Single-port versus multi-port robotic-assisted partial nephrectomy in perioperative, oncological, and renal function outcomes: a systematic review and meta-analysis.

Sike He, Dingbang Liu, Jinge Zhao, Zhenhua Liu, Ning Luo, Bo Li, Yaguang Wang, Jinsong Zhang, Hao Zeng, Guangxi Sun

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Journal of robotic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sike He *Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Dingbang Liu *Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Jinge ZhaoDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Zhenhua LiuDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Ning LuoNuclear Power Institute of China, Chengdu, 610213, China.
Bo LiNuclear Power Institute of China, Chengdu, 610213, China.
Yaguang WangNuclear Power Institute of China, Chengdu, 610213, China.
Jinsong ZhangNuclear Power Institute of China, Chengdu, 610213, China. zhangjs@npic.ac.cn.
Hao ZengDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China. kucaizeng@163.com.
Guangxi SunDepartment of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China. sungx077@126.com.

Funding

China National Nuclear Corporation 1-KJ-FWHT-WU-20240149China National Nuclear Corporation 1-KJ-FWHTWU-20240152Nature Science Foundation of Sichuan Province 24NSFSC5394
6 · The paper itself

Abstract

As a novel surgical method for partial nephrectomy (PN), single-port robot-assisted partial nephrectomy (SP-RAPN) is becoming widely used. The efficacy and safety outcomes comparison between SP-RAPN and traditional multi-port RAPN (MP-RAPN) is still unclear. Hence, this study aims to compare the perioperative, oncological, and renal function outcomes between SP-RAPN and MP-RAPN based on updated evidence. A literature search was performed online in Web of Science, PubMed, Embase, Cochrane Library, and ClinicalTrials.gov, and eligible studies were selected based on the criteria. The quality assessment of the included studies was performed by using the revised Cochrane Collaboration Risk of Bias Tool for randomized-controlled studies and the Newcastle-Ottawa Quality Assessment Scale for cohort studies. Effect sizes were calculated as odds ratios (ORs) for binary outcomes and as standard mean differences (SMDs) for continuous outcomes. All statistical analyses were conducted using Review Manager (version 5.4). 16 studies involving 2426 patients were finally analyzed. Compared to MP-RAPN, SP-RAPN shows lower off-clamp rate (OCR) (OR = 2.36, 95% confidence interval [CI]: 1.09, 5.12), less estimated blood loss (EBL) (SMD = -0.22, 95% CI: -0.38, -0.06), reduced length of hospital stay (SMD = -0.58, 95% CI: -0.91, -0.25), higher same-day discharge rate (OR = 3.62, 95% CI: 1.85, 7.09), lower positive surgical margin (OR = 0.67, 95% CI: 0.47, 0.96), and lower postoperative creatinine (SMD = -0.53, 95% CI: -0.86, -0.20). In addition, SP-RAPN has longer warm ischemia time (WIT) (SMD = 0.31, 95% CI: 0.07, 0.55) and less trifecta achievement (OR = 0.56, 95% CI: 0.34–0.97). No significant differences were found between operation time (OT), perioperative complications rate, intraoperative transfusion, intraoperative conversion, readmission after discharge, pain score, perioperative morphine milligram equivalent use, tumor recurrence rate, and other renal function outcomes. Large heterogeneity was found in OT, OCR, WIT, and EBL. As an alternative to MP-RAPN, SP-RAPN presents acceptable efficacy and safety. However, its influence on WIT, trifecta achievement, and renal function needs cautious assessment. More well-designed, prospective RCTs are vital to reinforce our findings.

Indexed as

KidneyKidney NeoplasmsNephrectomyRobotic Surgical ProceduresBlood Loss, SurgicalHumansLength of StayOperative TimeTreatment OutcomeMeta-analysisMulti-portRenal surgeryRobotic-assisted partial nephrectomySingle-port

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.